Protein Alignment slif and slc7a3a

DIOPT Version :9

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001007330.2
• Gene: slc7a3a / 492363
• ZFINID: ZDB-GENE-041114-206
• Length: 644
• Species: Danio rerio
• Alignment Length: 633
• Identity: 297/633 - (46%)
• Similarity: 403/633 - (63%)
• Gaps: 66/633 - (10%)

  Fly     1 MTNLWKALTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISF 65
            |.:....|.||:..|.:..|::.||.|:..||.|||||||||.|||||||:||...||||:.:.|
Zfish     5 MASFGHILLRRRALDFSGEETRFARCLSTLDLVALGVGSTLGAGVYVLAGEVAREKAGPAIVLCF 69

  Fly    66 LIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGY 130
            |:||::|..||:|||||.|||||.||||:|||||:||..||..||||||.||||||||||..|..
Zfish    70 LVAALSSMLAGLCYAEFGARVPKTGSAYLYSYVTVGEIWAFITGWNLILSYVIGTASVARAWSST 134

  Fly   131 FDSLINNNMSKALNESMHIDV--DFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLV 193
            ||:||...:|.....||.:.|  ..|.:|||..:..::|||..:||||..||:.:|.|||.:||:
Zfish   135 FDNLIEQKISNFFRASMAMKVPGKVLAEYPDLFALILILLLTGLLAFGVSESALVNKIFTGINLI 199

  Fly   194 TIAIVLVAGAMNANVDNWRI-------------PKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYG 245
            .:..::::|.:..|..||.:             |:: :...||:|||.|||:.|:::|||.|||.
Zfish   200 VLGFIIISGFVKGNTANWNLTYEYFINDTNITEPER-IESTFGSGGFAPFGLGGILSGAATCFYA 263

  Fly   246 FVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSV 310
            ||||||||||.|||.||.|:||:.||.||:|.|.:|||||..||:|:||||.:..:|.|.||..|
Zfish   264 FVGFDCIATTSEEAKNPMRSIPVGIVASLLICFFAYFGVSAALTLMMPYYKLNTQSPLPEAFSYV 328

  Fly   311 EWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIF 375
            .|...::||.:|::.||.|||||:|||:||::|||.:||:||:.||.:|..|||||||||.|||.
Zfish   329 GWAPARYIVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRSLSRMNKRTKTPLLATIASGIV 393

  Fly   376 ASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRY---------QDEEMTKLVSVKAPNVF-- 429
            |::||.||:|..|||:|||||||||::||:|||:|||         |.|::.:||..:...|.
Zfish   394 AALMAFLFDLAALVDLMSIGTLLAYSLVAVCVLILRYQPGNLSSSSQTEKLVELVGGEKVAVCGD 458

  Fly   430 --------------RQFFNGN-----SFREPNSMTSSI----TKVGIVVFAIFCLVWCS-LQKVF 470
                          ::.|...     |...|..|:.:|    |.:..|:..:.|:|... |:.:.
Zfish   459 SGDEYGVELDDSPRKEKFTAKLLLVPSKDSPTEMSGTIVYGTTAIISVLITVLCVVLAQRLESII 523

  Fly   471 DLDSTGGIVALSLVGAVLILICV----VIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLD 531
            :|:    ||.::.. .:|:|:||    ||..||.|...|||||||:|::|..|:|.|:|||.|||
Zfish   524 NLE----IVWVTAC-VILVLLCVLCVIVIFRQPESKEALTFKVPLLPWLPLFSIFVNIYLMMQLD 583

  Fly   532 LNTWIRFLIWIVIGYVIYFCYGMRNSTQISRS--RSHAEVAASALQNQ 577
            :.||.||.:|:.||:.|||.||:.:||:...|  |.:    ..||||:
Zfish   584 VATWCRFTVWMAIGFAIYFGYGIWHSTEAMNSSVRKY----EPALQNK 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	288/602 (48%)
		AA_permease_C	507..557	CDD:290617	28/49 (57%)
slc7a3a	NP_001007330.2	2A0303	4..611	CDD:273330	290/611 (47%)
		AA_permease_C	559..609	CDD:290617	28/49 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593064
Domainoid	1	1.000	463	1.000	Domainoid score	I454
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	557	1.000	Inparanoid score	I1071
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D421901at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm6524
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.840