DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and gb

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001287555.1	Gene:	gb / 43265	FlyBaseID:	FBgn0039487	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	117/549 - (21%)
Similarity:	211/549 - (38%)	Gaps:	131/549 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KALTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNI--AGPAVTISFLIA 68
            ||..|..:.:.:.....:.:.|.|.:..|:.:|...|.|::|....|...:  .|.::.| :::.
  Fly    38 KAQCREGSAESDSSRVVIKKQLGLLEGVAIILGIIFGSGIFVSPKGVIREVESVGASLVI-WVLC 101

  Fly    69 AIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDS 133
            .:.|....:||||....:||:|..|.|.:...|...||...|:.::.:|..|
  Fly   102 GLLSMIGALCYAELGTAIPKSGGDYAYIFEAYGSLPAFLYLWDAMMIFVPTT------------- 153

  Fly   134 LINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSF-------LNNIFTTVN 191
                |....|..:.::...|.|...:.....:.||.|..:.|....:|:       :.|:.....
  Fly   154 ----NAIMGLTFASYVLEPFFGGACEIPKIALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTK 214

  Fly   192 LVTIAIVLVAG---AMNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFY----GFVGF 249
            :..:.::::.|   .|..||:|:..|       |......|    |.|:.|   ||    .:.|:
  Fly   215 IAALVLIILVGLVWMMMGNVENFTRP-------FDNTETDP----GKMSVA---FYSGIFSYAGW 265

  Fly   250 DCIATTGEEAINPKRNIPLSIVVSL-------IIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAF 307
            :.:....||..:|.||:|.:|.:||       ::..::|..|.:...|:              |.
  Fly   266 NYLNFMTEELRDPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEMI--------------AS 316

  Fly   308 DSVEWYTIKWIVTIG----AVFALCTSLLGA----------MFPLPRILYAMGKDGILFKRLS-- 356
            :::       .||.|    .||:|...|:.|          :....||.:...::|.:...||
  Fly   317 NAI-------AVTFGDKILGVFSLIIPLMVAISAFGGLSVHIMTSSRICFVGARNGHMPAILSHI 374

  Fly   357 TVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDEEMTKLV 421
            :|.|||..|.|..:   .|.||:.::        :..:..|:.|..:.          |....::
  Fly   375 SVKSYTPLPSLVFL---CFLSIVMLV--------VSDVYVLITYASIV----------ESFFIML 418

  Fly   422 SVKAPNVFRQFFNGNSFREPNSMTSSITKVGIVVFAIFCLVWCSLQKVFDL----DSTGGIVALS 482
            ||.|...||       :..| .|...| ||.:.:.|:|.:| |:...|..:    ...|..|.::
  Fly   419 SVSAVLYFR-------YTRP-CMERPI-KVAMWIPALFVIV-CAFLVVVPIYVAPYEVGMGVLIT 473

  Fly   483 LVGAVLILICVVIGMQP---VSTIE-LTF 507
            ::|.....:.||...:|   .|||: :||
  Fly   474 IIGIPFYYVGVVWKNKPKWVQSTIDSVTF 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	115/547 (21%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	1/1 (100%)
gb	NP_001287555.1	2A0308	32..515	CDD:273332	117/549 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910