Protein Alignment slif and slc7a1b

DIOPT Version :10

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001315138.1
• Gene: slc7a1b / 406380
• ZFINID: ZDB-GENE-040426-2105
• Length: 647
• Species: Danio rerio
• Alignment Length: 614
• Identity: 298/614 - (48%)
• Similarity: 403/614 - (65%)
• Gaps: 54/614 - (8%)

  Fly     1 MTNLWKALTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISF 65
            |..|.|.|.|.|..|.:..||:|:|.||.|||.|||||||||.|||||||.||...||||:.:||
Zfish     6 MKELGKQLLRVKVVDCSTEESRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVLSF 70

  Fly    66 LIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGY 130
            ||||:||..||:|||||.||||:.||||:|||||:||..||..||||||.|:|||:||||..|..
Zfish    71 LIAALASVMAGLCYAEFGARVPRTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSAT 135

  Fly   131 FDSLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTI 195
            ||.||..::.:.....|.|:...|.:|||..:..::|.|..:||||.|||:.:|.:||.||::.:
Zfish   136 FDELIGKHIEEFCRRHMSINTPGLAEYPDMFAVIIILTLTGLLAFGVKESAMVNKVFTCVNVLVL 200

  Fly   196 AIVLVAGAMNANVDNWRIPKKDV---------------PEGFGTGGFMPFGIAGVMAGAAKCFYG 245
            ..|:|:|.:...:.||.:..:|:               .|..|.|||||||.:||::|||.|||.
Zfish   201 MFVVVSGLIKGTLQNWNLNPEDILNHTTSANVSVPLPTEESLGFGGFMPFGFSGVLSGAATCFYA 265

  Fly   246 FVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSV 310
            |||||||||||||..||:|.||:.||.||:|.|::|||||..||||:|||..||::|.|.||..|
Zfish   266 FVGFDCIATTGEEVKNPQRAIPIGIVASLLICFVAYFGVSAALTMMMPYYMLDKNSPLPVAFKYV 330

  Fly   311 EWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIF 375
            .|....:.|.:|::.||.|||||:|||:||:::||.:||:|||.|:.::..:|||::||:.|||.
Zfish   331 GWEGATYAVAVGSLCALSTSLLGSMFPMPRVIWAMAEDGLLFKFLANISEKSKTPIMATVTSGIV 395

  Fly   376 ASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDE--------------EMTKLVSVKAP 426
            |:|||.||:|..|||:||||||||||:||.||||||||.|              |.|:..|:...
Zfish   396 AAIMAFLFDLKDLVDLMSIGTLLAYTLVAACVLVLRYQPEQPSVNVQYQRASCQEETEAESINES 460

  Fly   427 NVFRQFFNGNS------------FREPNSMTSSITKV-----GIVVFAIFCLVWCSLQKVFDLDS 474
            :.  .|..|:|            ..||:.::.....:     |::| .:||:|  ::|..|...:
Zfish   461 SA--GFLPGSSDLFSLRNLLSPQNEEPSRLSGLTVNICTSILGVLV-CVFCVV--AVQGGFQTWT 520

  Fly   475 TGGIVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDLNTWIRFL 539
            ...:::|:|   |.::|.::|..||.|..:|:|||||:||:|.||:|.|:|||.|||..||:||.
Zfish   521 LAVLISLAL---VCLIITLLIWRQPESKTKLSFKVPLLPFLPVLSMFINVYLMMQLDKGTWMRFA 582

  Fly   540 IWIVIGYVIYFCYGMRNSTQISRSRSHAE 568
            ||:|||::|||.||:.:||:.:.:||..|
Zfish   583 IWMVIGFIIYFGYGIWHSTEAALARSETE 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	290/594 (49%)
slc7a1b	NP_001315138.1	2A0303	8..602	CDD:273330	293/601 (49%)