Protein Alignment slif and Slc7a3

DIOPT Version :10

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_058913.2
• Gene: Slc7a3 / 29485
• RGDID: 68342
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 286/598 - (47%)
• Similarity: 401/598 - (67%)
• Gaps: 50/598 - (8%)

  Fly     4 LWKA-------LTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAV 61
            ||:|       |.||:..::..||::|||.|:..||.|||||||||.|||||||:||...|||::
  Rat     2 LWQALRRFGQKLVRRRVLELGMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKEKAGPSI 66

  Fly    62 TISFLIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARG 126
            .|.||:||::|..||:|||||.||||.:||||:|||||:||..|||.||||||.||||||||||.
  Rat    67 VICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARA 131

  Fly   127 LSGYFDSLINNNMSKALNESMHIDV-DFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTV 190
            .|..||:||.|::|:.|..::.::: ..|.:||||.:..:||||..:|..||.||:.:..:||.:
  Rat   132 WSSAFDNLIGNHISQTLKGTILLNMPHVLAEYPDFFALALVLLLTGLLVLGANESALVTKVFTGM 196

  Fly   191 NLVTIAIVLVAGAMNANVDNWRIPKKDV------------PEGFGTGGFMPFGIAGVMAGAAKCF 243
            ||:.:..|:::|.:...:.||::.|:|.            .:..|:|||||||:.|::.|||.||
  Rat   197 NLLVLGFVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCF 261

  Fly   244 YGFVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFD 308
            |.||||||||||||||.||:|:||:.||:||.|.||:|||||:.||:|:||||...::|.|.||.
  Rat   262 YAFVGFDCIATTGEEAQNPQRSIPMGIVISLSICFLAYFGVSSALTLMMPYYKLQPESPLPEAFS 326

  Fly   309 SVEWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSG 373
            .|.|...:::|.||::.||.|||||:|||:||::|||.:||:||:.|:.|::.|.||::||:|||
  Rat   327 YVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARVHNGTHTPIVATVVSG 391

  Fly   374 IFASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQ-DEEM-----------TKLVSVKAP 426
            :.|:.||.||.|..|||:|||||||||::|:||||:|||| |:||           .:.:..:..
  Rat   392 VIAAFMAFLFELTDLVDLMSIGTLLAYSLVSICVLILRYQPDQEMKNGEEEVELQEEETLEAEKL 456

  Fly   427 NVFRQFFNGNSFREPNSMTSSITKVG----IVVFAIFCLV---WCSLQKVFDLDSTGGIVALSLV 484
            .|...|...||.  |..::..|..|.    .|:..:.|||   |.:     .|.| |..|.:::|
  Rat   457 TVQALFCPVNSI--PTLLSGRIVYVCSSLLAVLLTVLCLVLTWWTT-----PLHS-GDPVWVTVV 513

  Fly   485 GAVLILICVVIGM---QPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDLNTWIRFLIWIVIGY 546
            ..:|.||..:.|:   ||.:...|.||||:||.:|.:|:|.|:|||.|:..:||.||.:|::||:
  Rat   514 VLILGLILGISGVIWRQPQNRTPLHFKVPVVPLLPLVSIFVNVYLMMQMTADTWARFGVWMLIGF 578

  Fly   547 VIYFCYGMRNSTQ 559
            .|||.||:::|.:
  Rat   579 AIYFGYGIQHSVE 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	282/583 (48%)
Slc7a3	NP_058913.2	2A0303	4..591	CDD:273330	284/594 (48%)