Protein Alignment slif and Slc7a1

DIOPT Version :10

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001386911.1
• Gene: Slc7a1 / 25648
• RGDID: 3716
• Length: 624
• Species: Rattus norvegicus
• Alignment Length: 631
• Identity: 281/631 - (44%)
• Similarity: 389/631 - (61%)
• Gaps: 73/631 - (11%)

  Fly     1 MTNLWKALTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISF 65
            :.:|.:.:.|||..|.:..||:|:|.||.:||.|||||||||.|||||||.||...||||:.|||
  Rat     6 LLSLGQQMLRRKVVDCSREESRLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISF 70

  Fly    66 LIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGY 130
            ||||:||..||:||.||.|||||.||||:|||||:||..||..||||||.|:|||:||||..|..
  Rat    71 LIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSAT 135

  Fly   131 FDSLINNNMSKALNESMHIDV-DFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVT 194
            ||.||...:.:...:.|.::. ..|...||..:..::::|..:|..|.|||:.:|.|||.:|::.
  Rat   136 FDELIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLV 200

  Fly   195 IAIVLVAGAMNANVDNWRIPK---------KDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFD 250
            :..::|:|.:..:::||::.:         .|....:|.|||||||.:||::|||.|||.|||||
  Rat   201 LCFIMVSGFVKGSIENWQLTENKSSPLCGNNDTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFD 265

  Fly   251 CIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWYTI 315
            ||||||||..||::.||:.||.||:|.|::|||||..||:|:||:..|.|:|.|.||....|...
  Rat   266 CIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDTDSPLPGAFKYRGWEEA 330

  Fly   316 KWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMA 380
            |:.|.:|::.||.|||||:|||:||::|||.:||:|||.|:.:|..||||::||:.||..|::||
  Rat   331 KYAVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMA 395

  Fly   381 MLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDEEMTKLVSVKAPNVFRQF------------- 432
            .||.|..|||:|||||||||::||.||||||||.|:         ||:..|.
  Rat   396 FLFELKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQ---------PNLVYQMARTTDELDQVDQN 451

  Fly   433 ------------------FNGNSFREPNSMTSS-----ITKVGIVVFAIFCLVWCSLQKVFDLDS 474
                              |:..:...|.:|..|     |..:...:.|:..:..|.:..:
  Rat   452 EMVSASESQTGFLPAAEKFSLKTILSPKNMEPSKFSGLIVNISAGLLAVLIITVCIVAVL----- 511

  Fly   475 TGGIVALS---------LVGAVLI--LICVVIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMF 528
              |..||:         :.|:||:  |:..:|..||.|..:|:||||.||.:|.||:|.|:|||.
  Rat   512 --GREALAEGTLWAVFVMTGSVLLCMLVTGIIWRQPESKTKLSFKVPFVPVLPVLSIFVNIYLMM 574

  Fly   529 QLDLNTWIRFLIWIVIGYVIYFCYGMRNSTQISRSRSHAEVAASAL 574
            |||..||:||.:|::||:.|||.||:.:|.:.|.:...|:...|.|
  Rat   575 QLDQGTWVRFAVWMLIGFAIYFGYGVWHSEEASLAAGQAKTPDSNL 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	275/605 (45%)
Slc7a1	NP_001386911.1	2A0303	4..605	CDD:273330	277/614 (45%)