DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and SPAPB24D3.02c

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_593989.1	Gene:	SPAPB24D3.02c / 2543419	PomBaseID:	SPAPB24D3.02c	Length:	543	Species:	Schizosaccharomyces pombe

Alignment Length:	557	Identity:	125/557 - (22%)
Similarity:	220/557 - (39%)	Gaps:	106/557 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RRKTEDVNEGESQLAR----------VLNL---------FDLTALGVGSTLG-LGVY-VLAGQVA 53
            :::..|::.|:.::..          :|||         |.|.|: .|.:.| :|:. .|.|.:|
pombe     8 KKEFHDISVGDIEVGESAPVTEDDKMLLNLGYKQEFKREFSLLAV-FGQSFGSMGLCPSLVGSMA 71

  Fly    54 F--NIAGPAVTISFLIAAIASAFAGICYAEFAARVPKAGSAYVY-SYVTIGEFVAFT---IGWNL 112
            |  |.....:..|:.:.|..........:|.|:.:|.:||.|.: :|::..::.||.   :|:.|
pombe    72 FSMNCGAGGMVWSWFVGATCLLPIAFALSELASSMPTSGSLYFWTAYLSPPKYRAFLSWFLGYVL 136

  Fly   113 ILEYVIGTAS---VARGLSGYFDSLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILA 174
            .|.|..|.||   .|.||.....|:.|.:.:....|...|.|        .|||....|:.....
pombe   137 ALAYSTGFASTIYAAAGLVQATASVANPSYAPTKYEEYGIYV--------ALSFACSALIVLPTK 193

  Fly   175 FGAKESSFLNNIFTTVNLVTIAIVLVAGAMNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGA 239
            |.|:.|||  |:...:..:.|.|:.:|.:..:...|             ||.:: ||.....:|.
pombe   194 FLARFSSF--NVVFQICTILIFIISLAASSTSETRN-------------TGSYI-FGNFENYSGW 242

  Fly   240 AKCFYGFV-----------GFDCIATTGEEAINPKRNIPLSIVVSLII-IFLSYFGVSTVLTMML 292
            ....:.|:           ||:..||..|||.|..:..|::|:.||.: :|:.:..:.|:...|.
pombe   243 TNMGWSFILCFTTPVWVLSGFESCATIVEEAKNASKAAPIAIISSLTVSLFMGFCIMITIAGTMG 307

  Fly   293 PYYKQDKDAPFPHAFDSVEWYTI--KWIVTIGAV--FALCTSLLGAMFPLPRILYAMGKD-GI-- 350
            ..:....:.|:......|.:..:  :..|.:.||  .|||.:.........|.::|..:| |:
pombe   308 HDFSSILNTPYGEPVSQVLYNNLGKRGAVGVSAVLIIALCFNCSALCLASSREIFAFARDKGLPG 372

  Fly   351 --LFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQ 413
              :|::|:...    .||.|.::..::..|:.:|    .||::.:|.::....|:|.
pombe   373 SWIFRKLTPGG----IPLNAILLVNLYTIIVGLL----MLVNVTAISSIFNLAIIAF-------- 421

  Fly   414 DEEMTKLVSVKAPNVFRQFFN----GNSFREPNSMTSSITKVGIVVFAIFCLVWCSLQKVFDLDS 474
                  .:|...|.|.|..||    |..:....|...||..|..:.|....|::.|.|....::.
pombe   422 ------FISYSLPLVCRLLFNRLNPGKFYCGKFSKPISIVAVAWLWFMALMLLFPSYQNPNKVEM 480

  Fly   475 TGGIVALSLVGAVLILICVVIGMQPVSTIELTFKVPL 511
            ...||.|...    :..||.....|....:..||.|:
pombe   481 NWAIVVLGFT----VFFCVGYYYLPKYGGKTFFKGPV 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	125/557 (22%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	3/5 (60%)
SPAPB24D3.02c	NP_593989.1	2A0304	34..512	CDD:273331	122/528 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I2865
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030