DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and isp5

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_595000.1	Gene:	isp5 / 2543028	PomBaseID:	SPAC1039.09	Length:	580	Species:	Schizosaccharomyces pombe

Alignment Length:	439	Identity:	93/439 - (21%)
Similarity:	159/439 - (36%)	Gaps:	96/439 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EGESQ-LARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIASAFAGICYA- 80
            :|:.| |.|.|....:..:|:|..:|.||:|  |.......|.|.::....:.:.|......|:
pombe    73 DGKPQKLKRTLTARHIQMIGIGGAIGTGVWV--GSKNTLREGGAASVLICYSLVGSMVLMTVYSL 135

  Fly    81 -EFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYV------IGTASVARGLSGYFDSLINNN 138
             |.|...|..||.:.|....|.....||:|||.:..::      :.|||:.      ....||
pombe   136 GELAVAFPINGSFHTYGTRFIHPSWGFTLGWNYLASFLATYPLELITASIC------LQFWIN-- 192

  Fly   139 MSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAK---ESSFLNN---IFTTVNLVTIAI 197
                :|..:.|.|             .:.||..:..||.:   |..|..:   :...|..:...|
pombe   193 ----INSGIWITV-------------FIALLCFVNMFGVRGYGEVEFFVSSLKVMAMVGFIICGI 240

  Fly   198 VLVAGAMNAN----VDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEE 258
            |:..|.:..:    :......|.....||       .|...|.:.||   :.:.|.:.|.....|
pombe   241 VIDCGGVRTDHRGYIGATIFRKNAFIHGF-------HGFCSVFSTAA---FSYAGTEYIGIAASE 295

  Fly   259 AINPKRNIP-----LSIVVSLIIIFLSYFGVSTVL------------TMMLPYYKQDKDAP---F 303
            ..||.:..|     :.|.|||..| |:.|.||.::            |...|:.....||.   .
pombe   296 TKNPAKAFPKAVKQVFIRVSLFYI-LALFVVSLLISGRDERLTTLSATAASPFILALMDAKIRGL 359

  Fly   304 PHAFDSVEWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLA 368
            ||..::|            .:.::.|:..|..:...|.|::|.:.|...|....|:...: ||||
pombe   360 PHVLNAV------------ILISVLTAANGITYTGSRTLHSMAEQGHAPKWFKYVDREGR-PLLA 411

  Fly   369 TIVSGIFASIMAMLFN------LDQLVDMMSIGTLLAYTIVAICVLVLR 411
            ......|.::..:..:      .|.|:.:.::.||..:..:.:..::.|
pombe   412 MAFVLCFGALGYICESAQSDTVFDWLLSISNLATLFVWLSINVSYIIYR 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	93/439 (21%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
isp5	NP_595000.1	LysP	37..579	CDD:223903	93/439 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I1891
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.960