DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and SPBPB2B2.01

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_596849.1	Gene:	SPBPB2B2.01 / 2541403	PomBaseID:	SPBPB2B2.01	Length:	585	Species:	Schizosaccharomyces pombe

Alignment Length:	490	Identity:	94/490 - (19%)
Similarity:	183/490 - (37%)	Gaps:	103/490 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIASAFAG 76
            |.:..:.|:. |.|.|....:..:|:|..:|.||:|.:.:..:.....:|.|.:.|.........
pombe    69 KNQQDSAGQG-LKRRLKSRHIQMIGIGGAIGTGVWVGSSKSLYRGGAASVLIDYCIVGTMVFCTV 132

  Fly    77 ICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVI--------GTASVARGLSGYFDS 133
            ....|.|...|..||...::...|.|...|.:.||.:..:::        ||..:.     |:.:
pombe   133 YALGELAVAFPTRGSFVTHATRFIDESWGFALSWNYVFSFIVTIPLELTTGTMMIK-----YWTN 192

  Fly   134 LINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIV 198
                     ||..:.:.|             .::.|..|..||.|....:..|.:|:.:|.:...
pombe   193 ---------LNSGIWVTV-------------FIVFLFFINIFGVKGYGEMEFIMSTIKVVAMCGF 235

  Fly   199 LVAGAMNANVDNWRIPKKDVPEGF-GTGGFMP-------FGIAGVMAGAAKCFYGFVGFDCIATT 255
            ::.|.:   :|...:|...  .|: ||..|..       .|...|...||   :.|.|.:.:...
pombe   236 IILGII---IDCGGVPTDH--RGYMGTHIFRENAFRHKFKGFCAVFTSAA---FSFSGTEYVGVA 292

  Fly   256 GEEAINPKRNIPLSI-----------VVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDS 309
            ..|..||.:..|:::           ::||.|:.|...|....||   .|:..|. :||..|...
pombe   293 AAETENPAKAFPVAVRQTLFRIAIFYILSLFIVSLLISGADPRLT---SYHGVDA-SPFVLAIKD 353

  Fly   310 VEWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGI 374
            .....:..|:....:.::.:|....::...|.::::|.:|...|..:.|:...: ||:|.::..:
pombe   354 ANIKALPSILNAIILISVISSANAQLYAGSRAIHSLGCNGFAPKCFTLVDREGR-PLVALLILFL 417

  Fly   375 FASIMAMLFN------LDQLVDMMSIGTLLAYTIVAICVLVLRY------QDEEMTKLVSVKAPN 427
            |..:..::..      .|.::.:..:|||..:.  :||:..:||      |:..:.::..|...|
pombe   418 FMFLGYLVETGQYDTVFDWMLSISGLGTLFCWG--SICLAHIRYRAAMKHQNRSLKEVGFVSPFN 480

  Fly   428 VFRQFFNGNSFREPNSMTSSITKVGIVVFAIFCLV 462
            |:..::                     .|.:.|||
pombe   481 VYASYY---------------------AFILVCLV 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	94/490 (19%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
SPBPB2B2.01	NP_596849.1	LysP	36..584	CDD:223903	94/490 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I1891
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.960