DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and Slc7a9

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_446381.1	Gene:	Slc7a9 / 116726	RGDID:	619905	Length:	487	Species:	Rattus norvegicus

Alignment Length:	580	Identity:	116/580 - (20%)
Similarity:	221/580 - (38%)	Gaps:	146/580 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RRKTED---VNEGE---SQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNI--AGPAVTISFL 66
            ||:.||   |:..|   :.|.:.:.|.....:.||:.:|.|:::....|..|.  .||.:.| :.
  Rat     7 RRRREDEKSVHSTEPKTTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTESVGPCLII-WA 70

  Fly    67 IAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGW-NLILEYVIGTASVARGLSGY 130
            ...:.:....:|:||....:.|:|..|.|.....|...|:...| :||:......|.:....|.|
  Rat    71 ACGVLATLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEY 135

  Fly   131 FDSLINNNMSKALNESMHIDVDFLGDYP-----DFLSFGMVLLLAAILAFGAKESSFLNNIFTTV 190
            ..:..                 :||..|     ..|:...:||:..:.|...:..|::.|:||..
  Rat   136 VCAAF-----------------YLGCRPPAVVVKLLAAAAILLITTVNALSVRLGSYVQNVFTAA 183

  Fly   191 NLVTIAIVLVAGAM---NANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCI 252
            .||.:||::::|.:   ..||.|:    ::..||..|      .:..:........:.:.|::.:
  Rat   184 KLVIVAIIIISGLVLLAQGNVKNF----QNSFEGSQT------SVGSISLAFYNGLWAYDGWNQL 238

  Fly   253 ATTGEEAINPKRNIPLSIVVSL-------IIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSV 310
            ....||..||.||:|::||:.:       |::.::||.|.|...::       :.......|...
  Rat   239 NYITEELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELL-------QSQAVAVTFGDR 296

  Fly   311 EWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIF 375
            ..|...|:|.:...|:...:..|..|...|::|..|::|.:.|.||.::....||..|.:..||.
  Rat   297 VLYPASWVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVKRLTPAPALVFYGII 361

  Fly   376 ASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDEEMTKLVSVKAPNVFRQFFNGNSFRE 440
            |.|..:..:::.||:..|....|.|.:..:.::|:|:..:::.:  .:|.|
  Rat   362 AIIYIIPGDINSLVNYFSFAAWLFYGMTILGLVVMRFTRKDLER--PIKVP-------------- 410

  Fly   441 PNSMTSSITKVGIVVFAIFCLVWCSLQKVFDLDSTGGIVALSLVGAVLILICVVIGMQPVSTIEL 505
                             ||                        :..::||:.|.:.:.|:
  Rat   411 -----------------IF------------------------IPIIVILVSVFLILAPI----- 429

  Fly   506 TFKVPLVPFVPCLSVFANLYLMFQLDLNTWIRFLIWIVIGYVIYFC---YGMRNSTQISR 562
             ...|...::.|                     :::|:.|.:.||.   |..|.:.:|||
  Rat   430 -ISSPAWEYLYC---------------------VLFILSGLIFYFLFVHYKFRWAQKISR 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	113/573 (20%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	8/52 (15%)
Slc7a9	NP_446381.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23		6/15 (40%)
Slc7a9	NP_446381.1	2A0308	13..484	CDD:273332	112/574 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351264
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940