DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and slc7a13

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_002941804.3	Gene:	slc7a13 / 100495712	XenbaseID:	XB-GENE-995917	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	496	Identity:	125/496 - (25%)
Similarity:	206/496 - (41%)	Gaps:	81/496 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LARVLNLFDLTALGVGSTLGLGVYV----LAGQVAFNIAGPAVTISFLIAAIASAFAGICYAEFA 83
            |.|.|..||.|...||..:|.|::|    :......|: |.|:.| :....|......:||||..
Frog    23 LRRTLGFFDGTCFLVGIIVGAGIFVSPTGVLQYAQLNV-GVALCI-WAACGILVMMGALCYAELG 85

  Fly    84 ARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDSLINNNMSKALNESMH 148
            :.:|.||..|.:....:|.|.||...|.|||  .|..||               |.::||..:.:
Frog    86 SALPYAGGEYYHVKQALGPFPAFIFIWTLIL--FIRPAS---------------NAARALMFAEY 133

  Fly   149 IDVDFLGDYPDFLSFGMVLLLAAILAFG------AKESSFLNNIFTTVNLVTIAIVLVAGAMNAN 207
            ....|....|.......::.||.:...|      ||.::::.|:||.:.::.:.:::..|....
Frog   134 ATRPFFSGCPTPELLKKIVALAVLWVLGIINTKSAKTTTWVQNVFTVLKMLALILIVTCGLKEL- 197

  Fly   208 VDNWRIPKKDVPEGFGTGGFMP-FGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPLSIV 271
                 ..|.::|.........| ...|.:.....:..|.:.|::.:....||..||.:||||..:
Frog   198 -----AEKTEIPGHLQNAFSSPDLNAAQIAESFFQGLYAYGGWNYLNYIAEEIKNPTKNIPLCTI 257

  Fly   272 --VSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWY-----TIKWIVTIGAVFALCT 329
              ||::|:|.....:| .||::.|     |:. ...|..||.|.     .:.||:.:....::..
Frog   258 TAVSVVIVFYLLVNIS-YLTVLTP-----KEI-VSSAAVSVTWADRVIPMVAWIIPVSVAISIFG 315

  Fly   330 SLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSI 394
            :|.|.||.|.|:.||..|:|.|...||.::....||..|.|:|.|.|||..:..:|..|.:....
Frog   316 ALNGGMFMLGRLNYAGSKEGHLPSLLSMLHVNHLTPAPAMILSTIIASIFVIPSDLLSLTNYFGF 380

  Fly   395 GTLLAYTIVAICVLVLRYQDEEMTK-------------LVS--------VKAPNVFRQFFNGNSF 438
            .|.|...:..|.::||||::..:.:             ||:        :::|.|  |:|....|
Frog   381 STWLLVGLTVISLIVLRYREPNLPRPYKVFLPIAFGVVLVAAFLVLAPIIQSPKV--QYFYALLF 443

  Fly   439 REPNSMTSSITKVGIVVFAI----FCLVWCSLQKVFDLDST 475
                .::|.|.....|.|.:    |..:.|.||.:.::..|
Frog   444 ----MLSSMIIYFPFVYFKLRVPYFNAITCYLQLLMEVAPT 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	125/496 (25%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
slc7a13	XP_002941804.3	2A0308	17..477	CDD:273332	124/491 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910