Protein Alignment slif and slc7a2.2

DIOPT Version :10

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_017948087.1
• Gene: slc7a2.2 / 100494231
• XenbaseID: XB-GENE-5763997
• Length: 622
• Species: Xenopus tropicalis
• Alignment Length: 626
• Identity: 293/626 - (46%)
• Similarity: 401/626 - (64%)
• Gaps: 59/626 - (9%)

  Fly     3 NLWKALTRRKTEDVNEGE--SQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISF 65
            :.:|.|||.|...: |||  |.|.|.|:..||.|||||||||.|||||||:||...:||::.:||
 Frog     9 SFYKILTRTKQVTL-EGENSSNLCRCLSTLDLVALGVGSTLGAGVYVLAGEVAKVDSGPSIILSF 72

  Fly    66 LIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGY 130
            ||||:||..||:|||||.||||..||||:|||||:||..||..||||||.|||||:||||..|..
 Frog    73 LIAALASVLAGLCYAEFGARVPLTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSAT 137

  Fly   131 FDSLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTI 195
            ||.|:...:...|:.:||:|:..|.:|||..:..:::|||.:|:||.|||:.:|.:||.:|::.:
 Frog   138 FDDLVGKKIGNFLSNTMHMDLPGLAEYPDIFAVCLIILLAGLLSFGVKESTTVNKVFTAINILVL 202

  Fly   196 AIVLVAGAMNANVDNWRIPKKDV--------------PEG--FGTGGFMPFGIAGVMAGAAKCFY 244
            ..|:.:|.:..|:..|::.|:|:              ..|  ||.|||||||.:|.:||||.|||
 Frog   203 LFVIASGCVTGNIKYWKMSKEDLWVSKQTVSNHSIGNETGLDFGAGGFMPFGFSGTLAGAATCFY 267

  Fly   245 GFVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDS 309
            .|||||||||||||..||:::|||.||:||.|.|.:|||||..||:|:||:..|..:|.|.||:.
 Frog   268 AFVGFDCIATTGEEVKNPQKSIPLGIVLSLSICFFTYFGVSASLTLMMPYHLLDSQSPLPAAFEY 332

  Fly   310 VEWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGI 374
            |.|...|:||.:|::.||.|||||:|||:||||:||.:||:||:.||.::| .::|::||||||:
 Frog   333 VGWSVAKYIVAVGSLCALTTSLLGSMFPMPRILFAMARDGLLFQPLSRLSS-RQSPVIATIVSGV 396

  Fly   375 FASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDEEMTKLVSVKAPNVFRQFFNGNSFR 439
            .|::||.||:|..||||||||||||||:|:.|||:||||.:  |........|:..|  |.:|..
 Frog   397 VAALMAFLFDLKALVDMMSIGTLLAYTLVSTCVLLLRYQPQ--TDFGKSPDGNLPEQ--NISSLS 457

  Fly   440 EPNSMTSSITKVGIV---VFAIFCLVWCSLQKVFDLDSTGG-------------IVALSLVGAVL 488
            .|.. |.|:....:|   |.||..|| |    |..:.||.|             ::.|||:|.:.
 Frog   458 HPPE-TPSVHSSALVTHCVLAITLLV-C----VASVVSTAGSQCLLSGKAWCLSLLVLSLLGIIT 516

  Fly   489 ILICVVIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDLNTWIRFLIWIVIGYVIYFCYG 553
            .|  |:|..||.:..:.||.||.||.:|.:|:..|:|||.||..:||.|:.:|:.:|:||||.||
 Frog   517 AL--VIIWRQPQNQSKATFMVPFVPVLPVVSILVNIYLMVQLSTDTWYRYAVWMAVGFVIYFGYG 579

  Fly   554 MRNSTQ-----------ISRSRSHAEVAASALQNQGQHVNP 583
            :|:|.:           ::.|.:.. ..|:.|:.|.....|
 Frog   580 IRHSIERLQLMDKCTQKVAISSTETXCKANCLELQLGEAKP 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	286/582 (49%)
slc7a2.2	XP_017948087.1	2A0303	5..585	CDD:273330	288/589 (49%)