DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and XB985134

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_017950392.2	Gene:	XB985134 / 100492274	XenbaseID:	XB-GENE-985135	Length:	503	Species:	Xenopus tropicalis

Alignment Length:	525	Identity:	115/525 - (21%)
Similarity:	207/525 - (39%)	Gaps:	115/525 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTNLW------KALTRRKTEDVNEG-------ESQLARVLNLFDLTALGVGSTLGLGVYVL-AGQ 51
            |:.||      |..|:.|.:..|.|       :.|:.:.:.||:..:|.||:.:|.|::|. .|.
Frog     1 MSTLWDLFCSRKMHTKSKEKRANGGPGKNEPEKMQMKQEITLFNGVSLIVGNMIGSGIFVSPKGV 65

  Fly    52 VAFNIAGPAVTISFLIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWN--LIL 114
            :.::.:.....|.:.:..:.|.|..:||||....|.|:|::|.|.....|.|:||...|:  ||:
Frog    66 LMYSTSFGLSLIIWALGGMFSMFGALCYAELGTSVIKSGASYAYILEAFGGFIAFIRLWSSLLII 130

  Fly   115 EYVIGTASVARGLSGYFDSLINNNMSKALNESMHIDVDFLGDYPDFLS----FGMVLLLAA---- 171
            |... .|.:|...:.|...                        |.|||    :..|.|:||
Frog   131 EPTT-QAIIAITFANYIVQ------------------------PIFLSCQPPYAAVRLIAAACIC 170

  Fly   172 ----ILAFGAKESSFLNNIFTTVNLVTIAIVLVAG---AMNANVDNWRIPKKDVPEGFGTGGFMP 229
                |.....:..:.:.::||...::.:.:::..|   .:....||.:.|.    ||..|
Frog   171 TLTFINCVHVRWGTRVQDVFTYAKIMALIMIISVGLAKIVQGESDNLKNPF----EGSTT----- 226

  Fly   230 FGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPY 294
             .|..:........|.:.|:|.:....||..:|:||:||:|.:|:.::.:.|      |...:.|
Frog   227 -NIGSMALSLYSALYSYSGWDTLNFVTEEMKHPERNLPLAIAISMPVVTIIY------LLTNVAY 284

  Fly   295 YKQDKDAPFPHAFDSVE--------WYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGIL 351
            |.. .|.|...|.|:|.        .|. ||::.|....:....|..::....|:.|...:.|.|
Frog   285 YAV-LDMPDVLASDAVAVTFGNEVLGYA-KWLIPIAVAMSCYGGLNSSIIAASRLFYVGARQGHL 347

  Fly   352 FKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDEE 416
            ...||.::....||:.|.:.:|:.|.:..::.::..|::..|....|...:....::|||....:
Frog   348 PASLSLIHVENFTPVPALLFNGLIAILYLLVEDVFLLINYYSFSYWLFVGLSVAGLIVLRITQPQ 412

  Fly   417 MTKLVSVKAPNVFRQFFNGNSFREPNSMTSSITKVGIVVFAIFCLVWCSLQKVF---DLDSTGGI 478
            ..:.|                            ||.:....::||  |||..||   ..|:|..:
Frog   413 RERPV----------------------------KVNLFFPVVYCL--CSLFLVFVPIYCDTTNSL 447

  Fly   479 VALSL 483
            :.:.:
Frog   448 IGIGI 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	111/512 (22%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
XB985134	XP_017950392.2	2A0308	13..490	CDD:273332	111/513 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920