Protein Alignment slif and slc7a3b

DIOPT Version :9

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_001342962.3
• Gene: slc7a3b / 100003376
• ZFINID: ZDB-GENE-120813-6
• Length: 698
• Species: Danio rerio
• Alignment Length: 650
• Identity: 306/650 - (47%)
• Similarity: 406/650 - (62%)
• Gaps: 73/650 - (11%)

  Fly     1 MTNLWKALTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISF 65
            :.:..|.|.||:..|.:..||..||.|...||.|||||:|||.|||||||:||...||||:.:||
Zfish    58 LASFGKMLLRRRVLDDSPVESHFARCLTTLDLIALGVGATLGAGVYVLAGEVAREKAGPAIVLSF 122

  Fly    66 LIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGY 130
            ||||::|..||:|||||.|||||.||||||||||:||..||..||||||.||||||||||..|..
Zfish   123 LIAALSSVLAGLCYAEFGARVPKTGSAYVYSYVTVGEIWAFITGWNLILSYVIGTASVARAWSAT 187

  Fly   131 FDSLINNNMSKALNESMHI--DVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLV 193
            ||||:...:|......|..  ..:.|..|||..:..:|:||..:||||..||:.:|.|||.:|||
Zfish   188 FDSLLAQKISTFFKAFMSFPDTQNVLAKYPDVFALILVMLLTGLLAFGVSESALVNKIFTGINLV 252

  Fly   194 TIAIVLVAGAMNANVDNWRIPKKD------------VPEGFGTGGFMPFGIAGVMAGAAKCFYGF 246
            .:..|:::|.:..:..||.:..:|            :.:.||:|||.|||:.||::|||.|||.|
Zfish   253 VLTFVIISGFVKGDTANWNLTVEDYINRTNITGAQKIEKEFGSGGFAPFGLNGVLSGAATCFYAF 317

  Fly   247 VGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVE 311
            |||||||||.|||.||.|:||:.||.||:|.|.:|||||..||:|:|||..||.:|.|.|||.|.
Zfish   318 VGFDCIATTSEEAKNPMRSIPIGIVASLLICFFAYFGVSAALTLMMPYYMLDKHSPLPQAFDYVG 382

  Fly   312 WYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFA 376
            |...::||::|::.||.|||||:|||:||::|||.:||:||:.||.::..||||.|||:||||.|
Zfish   383 WGPARYIVSVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRFLSRMHKKTKTPALATLVSGIVA 447

  Fly   377 SIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQ---------DEEMTKLVSVKAPNVFRQF 432
            ::||.||:||.|||:||||||||||:||:|||:||||         |.:..:|..::|..|. ..
Zfish   448 ALMAFLFDLDALVDLMSIGTLLAYTLVAVCVLILRYQPSRLGSSGADVKPVELQRLEAKAVM-DV 511

  Fly   433 FNGNSFRE-----PNSMTSSI-----------TKV-GIVV----------FAIFCLVWCSLQKVF 470
            .:|:.:.:     |.....||           ||: ||:|          |.:.|||   |....
Zfish   512 DSGDEYSQDMETIPLKKRFSIRMLVQPICDVPTKISGIIVYSACGTISVLFTLLCLV---LSVCL 573

  Fly   471 DLDSTGG--IVALSLVGAVLILIC-VVIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDL 532
            :..:.|.  .:.|.::.:||..:| |||..||.|...|||||||:|.:|.:|:|.|:|||.|:..
Zfish   574 EQVAMGHPLFICLVVLLSVLSTVCIVVIWRQPQSKEALTFKVPLLPILPLISIFVNIYLMMQMSG 638

  Fly   533 NTWIRFLIWIVIGYVIYFCYGMRNSTQISRSRSHAEVAASALQNQGQHVNP---GFEPDYKVENG 594
            .|||||.:|:.||::|||.||:|:|::             ...|..|...|   |.:|.|..|:|
Zfish   639 ATWIRFAVWMAIGFLIYFAYGIRHSSE-------------GKNNSPQKFEPILQGKKPIYLAEDG 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	296/601 (49%)
		AA_permease_C	507..557	CDD:290617	28/49 (57%)
slc7a3b	XP_001342962.3	2A0303	57..665	CDD:273330	298/610 (49%)
		AA_permease_C	613..663	CDD:290617	28/49 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593061
Domainoid	1	1.000	463	1.000	Domainoid score	I454
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	557	1.000	Inparanoid score	I1071
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D421901at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm6524
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.840