Protein Alignment CYP4F3 and Cyp9f2

DIOPT Version :9

• Sequence 1: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_650189.1
• Gene: Cyp9f2 / 41520
• FlyBaseID: FBgn0038037
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 425
• Identity: 96/425 - (22%)
• Similarity: 180/425 - (42%)
• Gaps: 76/425 - (17%)

Human   133 GDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN----ESVNIMHAKWQLLASEGSAR----- 188
            |..|......:|...|..|:|||..:.::...::.|    |:|:.:        .:..:|
  Fly   123 GSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCL--------KQDDSRVQENE 179

Human   189 LDMFEHISLMTLDSLQKCVFSFD-SHCQEKPSEYIAAILELSALVTKRHQQILLYI--------- 243
            |||.::.:..|.|.:....|... :..:::.:.:.....:|:.....:..:.:|:.
  Fly   180 LDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKIL 244

Human   244 ----------DFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDF 298
                      .:...|..|..::|:...:|......::.|.|..:.::        |.|:..:
  Fly   245 KVELFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTE--------KTKASAV-- 299

Human   299 IDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLK 363
                        ::.||.||.|:...|.|.|.:|:|..:.:..:.|.::.:.|:|..:|||::.:
  Fly   300 ------------REWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQ 352

Human   364 DREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP-DGR--VIPKGIICLISVF 425
            |.|.||:.::.:..:.:|...:.|.||..|...||.|.|.:||... ||:  .:.||.:..:...
  Fly   353 DLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTC 417

Human   426 GTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFR 490
            |.|.:|..:.:|..:||.||..:|.:...|..:.||..|.|||||..||:.|.|.|:...|..:|
  Fly   418 GFHRDPKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYR 482

Human   491 VLPDHTEPRRKP----ELV-----LRAEGGLWLRV 516
            .     .|.:|.    ||:     |..:||.|:::
  Fly   483 F-----APAKKSCIPLELITSGFQLSPKGGFWIKL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	96/422 (23%)
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	95/421 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810