Protein Alignment CYP4F3 and Cyp316a1

DIOPT Version :9

• Sequence 1: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_648129.2
• Gene: Cyp316a1 / 38840
• FlyBaseID: FBgn0035790
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 455
• Identity: 116/455 - (25%)
• Similarity: 197/455 - (43%)
• Gaps: 67/455 - (14%)

Human    89 CWWVGPWHAIVRIFHPTYIKPVLFAPAA-------IVPKD---KVFYSFLKPWLGDGLLLSAGEK 143
            ||          :||.      ||.|.|       ::..|   :..|..:|.||..|:|:...|:
  Fly    71 CW----------VFHR------LFIPLADLELSRQLLENDTHLETGYELMKDWLVGGVLMCQSEQ 119

Human   144 WSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARL-DMFEHISLMTLDSLQKCV 207
            |.:...:::..|....|:..:.:.......:   .|.||.:...:: |::..:|.:.||.:..
  Fly   120 WQKRHSLISGLFDKGNLEQLIDLSRHQTEQL---LQKLAKQADQKVFDIWYTVSPIVLDLMVM-- 179

Human   208 FSFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTD--- 268
                :.|..||| ||...:.:||.:..||...:.....|.|:|:....| :|..||:....|
  Fly   180 ----TTCGAKPSEEYSKNLKDLSEIYRKRFLSLQSANRFNYWLSSPFMR-KRQNRLIKRLNDEHN 239

Human   269 ---AVIQERRRTLPSQGVDDF-LQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEG 329
               |:.|.:.:.....|:|.: |:..........:::||.|||   .:|:.|:|..|.:|..:.|
  Fly   240 NLMAMHQSQNQLKIENGLDIYQLRPIPLKDHKSLLEILLESKD---PQLTGEEICGELNTCNYLG 301

Human   330 HDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPP 394
            :...:..|.:.|..:|::|..|::|..|    |...:.|:..| ||.:|.:|...:.|::||:||
  Fly   302 YQLCSPALCFCLVTIARNPSVQQKCLDE----LNLAQIKDQGW-DLEKLNYLDAVLHETMRLYPP 361

Human   395 VPAVSRCCTQDI-----VLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKER 453
            ...|.|...:|.     ::.|.. :|.|....|:::....|...:|....:|..|| |
  Fly   362 QVIVGRQLKKDFPYTHSIVGDAE-LPCGSEIYINLYELQRNEVRYPKANHFDAQRFLD------- 418

Human   454 SPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEP 518
            ||...:.:|.|||.|..:.|:|..:|.:|...|..|.|||...|.|....|||.:..|..|.::|
  Fly   419 SPPELLSYSLGPRCCPARKFSMQLLKTLLAPILANFEVLPYGDEVRLDLRLVLGSSNGFQLALKP 483

Human   519  518
              Fly   484  483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	114/450 (25%)
Cyp316a1	NP_648129.2	p450	33..466	CDD:299894	110/436 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820