Protein Alignment CYP4F3 and Cyp4p2

DIOPT Version :9

• Sequence 1: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 381
• Identity: 130/381 - (34%)
• Similarity: 206/381 - (54%)
• Gaps: 19/381 - (4%)

Human   123 VFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGS 186
            |.|:||.|:|..|:|.:..:||...|.|||..||.:||..:.:|| .||:..: :::|   .:..
  Fly   118 VIYNFLHPFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFV-SQFQ---GQNE 178

Human   187 ARLDMFEHISLMTLDSLQKCVFSFD-SHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLT 250
            ..:.:.:.||..||:|:.:...... ....||...|.|....:...:|:|....|.:.|.:|.:.
  Fly   179 VVVSLKDRISRFTLNSICETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVYNMF 243

Human   251 PDGQRFRRACRLVHDFTDAVIQERRRTL--------PSQGVDDFLQAKAKSKTLDFIDVLLLSKD 307
             .|.::..|.::||:|:..:|.:||..|        .:|..||.: ...:.|....:|.|:.: :
  Fly   244 -TGHKYNAALKVVHEFSREIIAKRRVLLEEELENRRATQTADDDI-CVIRKKRFAMLDTLICA-E 305

Human   308 EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
            :|| .:.|..|..|.||.|.||:|||:.||.:.|.:::.:...||.|.||:||.:.| :...:..
  Fly   306 KDG-LIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILD-DLSNLNL 368

Human   373 DDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDP 437
            ..|::|.:|...|||::||:|.:|.:.|...|:..|.:|.::||.....|.||..|.||..|..|
  Fly   369 SQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWESP 433

Human   438 EVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLP 493
            |.:.|.||.|:|..:|.|.|:||||||.||||||.:||.|||.::.:.|..|::||
  Fly   434 EEFRPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	130/381 (34%)
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	130/381 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154876
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2076
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.880