Protein Alignment CYP4F3 and Cyp9b1

DIOPT Version :9

• Sequence 1: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 459
• Identity: 106/459 - (23%)
• Similarity: 180/459 - (39%)
• Gaps: 64/459 - (13%)

Human    96 HAIVRIFH----------PTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
            |.:|.:|:          |..||.:........|..:......:..:.|.|.:...:.|...|.:
  Fly    69 HKLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRSV 133

Human   151 LTPAFHFNILKPYMKIFNES----VNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVF--- 208
            |||.|....::....:.|||    :..:.:...:.|.|.:..|||....:.::.|.:....|
  Fly   134 LTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGLK 198

Human   209 --SFDSHCQEKPSEYIAAILELS-ALVTKRHQQILL---YIDFLYYLTPDGQRFRRACRLVHDFT 267
              |||.  .|.....|...|..| .|...:....||   ..:|......|........|||.|
  Fly   199 VNSFDD--PENEFHTIGKTLAFSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVD-- 259

Human   268 DAVIQERRR---TLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEG 329
              .:|.|.:   |.|                 |.|.:|:.:|.|.....:|::|.|:...|.|..
  Fly   260 --AMQYREKHNITRP-----------------DMIQLLMEAKKESKDNWTDDEIVAQCFIFFFAA 305

Human   330 HDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPP 394
            .:..::.:....|.|.::.:.|||..:||:|..:..:...:.:|...::.::.|.|.||||....
  Fly   306 FENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTL 370

Human   395 VPAVSRCCTQDIVLPDGR-----VIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERS 454
            ..|..|.|.:|..|.|..     ....|....|.:.|.|.:...:|.|:.:||.||..:..|:..
  Fly   371 SAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLI 435

Human   455 PLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEG-------GL 512
            |..::||..|||:|||..:|:.:.|.:|...:|.:::   ...||...::...|.|       |.
  Fly   436 PYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKI---EASPRTTRDMWESARGFNIIPTTGF 497

Human   513 WLRV 516
            |:::
  Fly   498 WMQL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	106/456 (23%)
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	101/434 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810