Protein Alignment Ssl1 and GTF2H2C_2

DIOPT Version :9

• Sequence 1: NP_001262227.1
• Gene: Ssl1 / 40509
• FlyBaseID: FBgn0037202
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001035955.1
• Gene: GTF2H2C_2 / 730394
• HGNCID: 35418
• Length: 395
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 207/410 - (50%)
• Similarity: 278/410 - (67%)
• Gaps: 18/410 - (4%)

  Fly     5 EQEDQKEYRWETGYEKTWEAIKDDEDGMLDGAIAEIIQKAKRQRQAQKSKQNRLGMMRHMFVVLD 69
            ::|.::..|||.|||:|||.:|:||.|.|...|.:|:.||||:|..:...|.|||||||::||:|
Human     2 DEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVD 66

  Fly    70 CSESMSVPDLKPTRLRCTVKLLELFIEEFFDQNPISQLGLIALKAKRAEKVTELTGTSRVHLKAL 134
            .|.:|...||||.||.||:||||.|:||:||||||||:|:|..|:|||||:|||:|..|.|:.:|
Human    67 GSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSL 131

  Fly   135 ESLANVSLTSEPSLQNGLDLALKSLKVVPSHASREIVIIMGSLTTCDPVDINLTIDELKKEGIRC 199
            :...:::...||||.|.|.:|:::||.:|.|.|||::||..|||||||.:|...|..||...||.
Human   132 KEAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKAAKIRV 196

  Fly   200 SVISLSAEIHVARYLTQQTMGTFGAVLDDAHFRDQLMSQVDPPPAAKTQHNSLIRMGFP-HTKNE 263
            |||.||||:.|...|.::|.||:..:||::|:::.|...:.||||:.:...|||||||| ||...
Human   197 SVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHLSPPPASSSSECSLIRMGFPQHTIAS 261

  Fly   264 VEGKDAPLSMCMCHIENLEEPSELTTTGHHCPQCNSKYCELPVECQSCGLTLVSAPHLARSYHHL 328
            :..:||..|..|.|::...||. ||..|:.||||.:|||||||||:.||||||||||||||||||
Human   262 LSDQDAKPSFSMAHLDGNTEPG-LTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHL 325

  Fly   329 FPVPNFEELPFEAMPASSSDLTSDVRECYGCAKALGQGVDKVADKVVFRCGFCKQFFCVDCDIFI 393
            ||:..|:|:|.|..        :..|.||||     ||  ::.|:.|:.|..|:..||||||:|:
Human   326 FPLDAFQEIPLEEY--------NGERFCYGC-----QG--ELKDQHVYVCAVCQNVFCVDCDVFV 375

  Fly   394 HDTLHACVGC-NTIPGVDGL 412
            ||:||.|.|| :.||...|:
Human   376 HDSLHCCPGCIHKIPAPSGV 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssl1	NP_001262227.1	SSL1	10..407	CDD:227480	203/398 (51%)
		Ssl1	67..258	CDD:190848	97/190 (51%)
		C1_4	291..403	CDD:297864	61/111 (55%)
GTF2H2C_2	NP_001035955.1	Ssl1	64..255	CDD:367789	97/190 (51%)
		C1_4	288..388	CDD:352591	63/114 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2969
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	415	1.000	Inparanoid score	I1841
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54264
OrthoDB	1	1.010	-	-		D285146at33208
OrthoFinder	1	1.000	-	-		FOG0004477
OrthoInspector	1	1.000	-	-		otm42148
orthoMCL	1	0.900	-	-		OOG6_102284
Panther	1	1.100	-	-	LDO	PTHR12695
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1505
SonicParanoid	1	1.000	-	-		X3170
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	12.010