Protein Alignment CG11109 and NSUN6

DIOPT Version :10

• Sequence 1: NP_730761.1
• Gene: CG11109 / 40507
• FlyBaseID: FBgn0037200
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: XP_047280733.1
• Gene: NSUN6 / 221078
• HGNCID: 23529
• Length: 473
• Species: Homo sapiens
• Alignment Length: 478
• Identity: 189/478 - (39%)
• Similarity: 261/478 - (54%)
• Gaps: 54/478 - (11%)

  Fly     3 YPK---TPFLVNPLLEADILKVNSAALA---------PLLEWLCLTPKVTTYRVNTLRCSVDDFR 55
            :||   .|.:.|.|.|..:.|....||.         .||:.|...|..||.||||...||...:
Human     4 FPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASVQHVK 68

  Fly    56 KKLEEKLAIRYGVKSPRIYCLPNLPEMLCIDPLDSQLTKAVADSELKEVVVDTNCGAALLRGAHI 120
            ..|.::|..::...|..|...|:|.::|.|..:..:  |.:...:. |.:|...||.|:|||||:
Human    69 NLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPR--KNIKKQQC-EAIVGAQCGNAVLRGAHV 130

  Fly   121 YAPGVLAMESNTEREELVNVYADLDGKCKRGTVKRYESPNKVFLGTGKVLMQRYQLFNNAEK--- 182
            ||||:::.....:..::::||:|:.||||:| .|.::. .|||||.|...:.|.::|:...:
Human   131 YAPGIVSASQFMKAGDVISVYSDIKGKCKKG-AKEFDG-TKVFLGNGISELSRKEIFSGLPELKY 193

  Fly   183 PASGVAVEMQSNVSGVPTLGDLSSEDGLLQNLPSIVCVRVLDPQPGERILDMCAAPGNKTSHIAE 247
            ...|:.:.|...|...|:...:......||||||.:...||:|||||:|||:|||||.||:|||.
Human   194 VIRGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAA 258

  Fly   248 LMGDRGSVVALD---NSASRVRSMLPKLGHYKSITAHVFNSTEAVAADAPSAPVGEFTGPPFPCE 309
            ||.|:|.|:|||   |...:::.....|| ..||.|..|:.|:||..|......||   |||..|
Human   259 LMHDQGEVIALDKIFNKVEKIKQNALLLG-LNSIRAFCFDGTKAVKLDMVEDTEGE---PPFLPE 319

  Fly   310 SFDRILLDAPCSGLGNRPQLSC--SIKQVKVLSSYPHIQRRLFEQAVQLVRPGGILVYSTCTVTE 372
            |||||||||||||:|.||.::|  |:|:|   :||..:||:||..||||::|.|:|||||||:|.
Human   320 SFDRILLDAPCSGMGQRPNMACTWSVKEV---ASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITL 381

  Fly   373 DECECLVAWALRKFVELRLTDATPRWGGPGLPLPGFEACKSRLLQRFGPSG-------------- 423
            .|.|..|||||.||..|:|....|:.||.|:...|....:.:.||||.||.
Human   382 AENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREA 446

  Fly   424 --------ANADTVGFFIAKFQK 438
                    ||.|::|||||||.|
Human   447 RREDMLRLANKDSIGFFIAKFVK 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11109	NP_730761.1	PUA_NSun6-like	102..195	CDD:409292	33/95 (35%)
		RsmB	<207..439	CDD:439914	124/259 (48%)
NSUN6	XP_047280733.1	PUA_NSun6-like	113..206	CDD:409292	33/94 (35%)
		RsmB	<199..469	CDD:439914	126/276 (46%)