DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arf79F and TRIM23

DIOPT Version :9

Sequence 1:	NP_001097667.1	Gene:	Arf79F / 40506	FlyBaseID:	FBgn0010348	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_001647.1	Gene:	TRIM23 / 373	HGNCID:	660	Length:	574	Species:	Homo sapiens

Alignment Length:	164	Identity:	105/164 - (64%)
Similarity:	129/164 - (78%)	Gaps:	1/164 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWR 79
            |.|:|::.:|||.|||||||:|||..|.:..|||||||||||||||:.||:|||||:.|:||||:
Human   402 KMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWK 466

  Fly    80 HYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLG 144
            ||:.|||.::|||||:.|:||.||..||.::|.|.|||||:|||||||||:..|::..|||:.|.
Human   467 HYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLS 531

  Fly   145 LHSL-RNRNWYIQATCATSGDGLYEGLDWLSNQL 177
            ||.| ..|:||||...|.||.||||||||||.||
Human   532 LHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQL 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arf79F	NP_001097667.1	ARF	5..179	CDD:128474	105/164 (64%)
TRIM23	NP_001647.1	mRING-HC-C3HC3D_TRIM23_C-IX	28..77	CDD:319559
		Bbox2_TRIM23_C-IX_rpt1	123..172	CDD:380831
		Bbox2_TRIM23_C-IX_rpt2	174..223	CDD:380832
		BBC	226..370	CDD:128778
		ARF-like	390..574		105/164 (64%)
		ARD1	406..574	CDD:206723	103/160 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1362554at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820