Protein Alignment SPoCk and YPK9

DIOPT Version :9

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_014934.1
• Gene: YPK9 / 854466
• SGDID: S000005817
• Length: 1472
• Species: Saccharomyces cerevisiae
• Alignment Length: 1233
• Identity: 256/1233 - (20%)
• Similarity: 452/1233 - (36%)
• Gaps: 324/1233 - (26%)

  Fly    16 PASPGSTVLIES--------PTTSSGVRNRRSKIKGVDSKPNPQRTISHVKDSRAVPQNVKPG-- 70
            |.:....|:||:        |..........|.:...::.|||....:.:..|......:.|.
Yeast   356 PLAKAEWVVIENEFGEFVIQPIDRQWYNRPLSTVLPFENYPNPSYEPNDINLSHHHANEINPNVP 420

  Fly    71 -----KVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEML-LST-SESSTHSASE----VAGRLQ 124
                 :...:|....| .|::.:.|.|.|.      |:.: ||| |...|....|    ..|:.|
Yeast   421 ILITFEYRYIKFIYSP-LDDLFKTNNNWID------PDWVDLSTVSNGLTKGVQEDRELAFGKNQ 478

  Fly   125 VDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNPLILLLLGSALVSVIMKQFDDAV 189
            :::|  :|.|..      |..||:|                :|..:.    .:.|:|:...|:..
Yeast   479 INLR--MKTTSE------ILFNEVL----------------HPFYVF----QVFSIILWGIDEYY 515

  Fly   190 SITIAILIVVTVAFIQEYRSEK----SLEELKKLVPPECHC----LREGRLDTFLARELVPGDIV 246
            .....|.::..::.......:|    :|.|:...     ||    ||:....|..:.|||||||
Yeast   516 YYAACIFLISVLSIFDSLNEQKKVSRNLAEMSHF-----HCDVRVLRDKFWTTISSSELVPGDI- 574

  Fly   247 HLNVGDR----VPADVRLFEAVDLSIDESSFTGETEPARKI--TDVLL-------NNTNVKDHSN 298
             ..|.|.    :|.|..|..: |..::||..|||:.|..|.  |:..:       .:|.:....:
Yeast   575 -YEVSDPNITILPCDSILLSS-DCIVNESMLTGESVPVSKFPATEETMYQLCDDFQSTQISSFVS 637

  Fly   299 MKNIAFMGT-LVRCGNGKG------IVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLS 356
             |:..:.|| ::|.....|      :||.||..:..|.:.:.|   ..||.          ....
Yeast   638 -KSFLYNGTNIIRARIAPGQTAALAMVVRTGFSTTKGSLVRSM---VFPKP----------TGFK 688

  Fly   357 FY--SFLIIG---VIMLLGWL--------QGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGV 408
            ||  ||..||   :|.:.|:.        .|.....|...::.:....:|..||..:|:.....:
Yeast   689 FYRDSFKYIGFMSLIAIFGFCVSCVQFIKLGLDKKTMILRALDIITIVVPPALPATLTIGTNFAL 753

  Fly   409 MRMAKRNSIVKKLPT-VETLGCVNVICSDKTGTLTKN--EMTATIIITSDGYMADVTGAGYNDQG 470
            .|: |...|....|| :...|.::|:|.|||||||::  ::....|...:|......|...:|..
Yeast   754 SRL-KEKGIFCISPTRLNISGKIDVMCFDKTGTLTEDGLDVLGVQISEPNGVRGQKFGELLSDIR 817

  Fly   471 EI----HIRHCNN-VEMAKTN-ITNLLEIGAVCNNAYIQNGTLLGQPTEGALVAVA--------M 521
            ::    .:..|:: ::....| ..:||    .|::....:|.|||.|.:..:....        .
Yeast   818 QVFPKFSLNDCSSPLDFKSRNFFMSLL----TCHSLRSVDGNLLGDPLDFKMFQFTGWSFEEDFQ 878

  Fly   522 KNGMYATAENYVRIQEYPFSSEQKMMAVKCIHKYNNNKEEIF----------------------- 563
            |...::..|.......:|.:||   :....:|..:||:|..|
Yeast   879 KRAFHSLYEGRHEDDVFPENSE---IIPAVVHPDSNNRENTFTDNDPHNFLGVVRSFEFLSELRR 940

  Fly   564 ---------------FAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFLAEAYEIGRKGLRVLAL 613
                           |.|||.|.:...|.|     .|:|.    :.|.:...|.  ..|.||:|.
Yeast   941 MSVIVKTNNDDVYWSFTKGAPEVISEICNK-----STLPA----DFEEVLRCYT--HNGYRVIAC 994

  Fly   614 AKGRSM-----------------QDLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQE 661
            | |:::                 .:|.:.|.:...:..:....|:::.|..:.:|..|.|||...
Yeast   995 A-GKTLPKRTWLYSQKVSREEVESNLEFLGFIIFQNKLKKETSETLKSLQDANIRTIMCTGDNIL 1058

  Fly   662 TALAID-------------PSRRLQAVPTHAIP--AW------------PTAGGVPLCSASACCS 699
            ||:::.             ||  :...|.|..|  .|            .|...|.|       .
Yeast  1059 TAISVGREAGLIQCSRVYVPS--INDTPLHGEPVIVWRDVNEPDKILDTKTLKPVKL-------G 1114

  Fly   700 TNCLENAMKEIYLTALAQQGLPLVTANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRV 764
            .|.:|:..:..|..|::.....|:.                ::.:::.|..|:::..|.|::.|:
Yeast  1115 NNSVESLRECNYTLAVSGDVFRLLF----------------RDENEIPEEYLNEILLNSSIYARM 1163

  Fly   765 SPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTI 829
            ||..|.|::..||:....||..|||.||..|||.||:||::.:....|.......|.   :...:
Yeast  1164 SPDEKHELMIQLQKLDYTVGFCGDGANDCGALKAADVGISLSEAEASVAAPFTSKIF---NISCV 1225

  Fly   830 IAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPA---- 890
            :..|.||:...  :.:|..||..:..:|:..|.:..|....:.|...|.|:|::::..|.|
Yeast  1226 LDVIREGRAAL--VTSFACFQYMSLYSAIQFITITILYSRGSNLGDFQFLYIDLLLIVPIAICMS 1288

  Fly   891 QSLGVEPVDHDVLKQKPRNVKQPMITKSVVVNVLLSASIIVLGTL--WVFQREMA-------DGT 946
            .|...|.:|    |::|   ...:::..::|.:|:|..::.|...  |:..::|:       .|.
Yeast  1289 WSKSYEKID----KKRP---SANLVSPKILVPLLISVFLVFLFQFIPWIIVQKMSWYIKPIVGGD 1346

  Fly   947 LGKTKRDTTMTFTCFVFFDMFNALSCRSQTKSVFTIG------LTTNRMFLLAVAFSIIGQMLVV 1005
            ......|.|:.|    |...|..:    .|..|.::|      ::.|..|::.:..||...:|:
Yeast  1347 DAVQSSDNTVLF----FVSNFQYI----LTAIVLSVGPPYREPMSKNFEFIVDITVSIGASLLL- 1402

  Fly  1006 YFPPLQMVFQTEA-------LTP----YDIFFLV----SLTSSVLVVSEIKKWFERTMERKMY 1053
                  |...||:       |||    :.:|.:|    :..:.:.:...||.|.::....|.|
Yeast  1403 ------MTLDTESYLGKMLQLTPISNSFTMFIIVWVILNYYAQLYIPPSIKGWLKKKKSSKKY 1459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	232/1116 (21%)
		Cation_ATPase_N	112..179	CDD:279080	12/70 (17%)
		E1-E2_ATPase	191..425	CDD:278548	63/275 (23%)
		Cation_ATPase	496..579	CDD:289987	22/128 (17%)
		COG4087	<760..823	CDD:226572	23/62 (37%)
		Cation_ATPase_C	872..1044	CDD:279079	41/205 (20%)
YPK9	NP_014934.1	P-ATPase-V	307..1431	CDD:273738	250/1203 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910