Protein Alignment SPoCk and Atp13a3

DIOPT Version :9

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: XP_038944543.1
• Gene: Atp13a3 / 678704
• RGDID: 1590881
• Length: 1249
• Species: Rattus norvegicus
• Alignment Length: 1072
• Identity: 238/1072 - (22%)
• Similarity: 426/1072 - (39%)
• Gaps: 233/1072 - (21%)

  Fly   138 YRAKIIGHNELLLVAEDPTWKKYIEQFRNPLILLLLGSALVSVIMKQFDDAVSITIAILIVVTVA 202
            ||..:.|.|| :.|.....:|..|::..||..:.    .|.|||:...|:.....:||:::..|:
  Rat   182 YRKLLYGVNE-IAVKVPSVFKLLIKEVLNPFYIF----QLFSVILWSIDEYYYYALAIVVMSIVS 241

  Fly   203 FIQE-YRSEKSLEELKKLVPPECH-----CLREGRLDTFLARELVPGD--IVHLNVGDRVPADVR 259
            .|.. |...|....|..:|.....     |.....::...:.:|||||  |:.|| |..:|.|..
  Rat   242 IISSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMIIPLN-GTVMPCDAV 305

  Fly   260 LFEAVDLSIDESSFTGETEPARKITDVLLNNTNV----------KDHSNMKNIAFMGTLV---RC 311
            |.....: ::||..|||:.|   :|...|.|.:|          ...::.::..|.||.|   |.
  Rat   306 LINGTCI-VNESMLTGESVP---VTKTNLPNPSVDVKGMGEEQYSPETHKRHTLFCGTTVIQTRF 366

  Fly   312 GNG---KGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVIML-LGW- 371
            ..|   |.|||.||..:..|::.:.:...:.....|.:..         |.||:..|::. :|:
  Rat   367 YTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDA---------YLFLLCLVVVAGIGFI 422

  Fly   372 -------LQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGC 429
                   |..|.:.|:...|:.:....:|..||..:|..:.....|:.|..........:...|.
  Rat   423 YTIVNSILNEKEVQEIIIKSLDIITITVPPALPAAMTAGIVYAQRRLKKVGIFCISPQRINICGQ 487

  Fly   430 VNVICSDKTGTLTKNEMTATIIITSDGYMADVTGAGYNDQGEIHIRHCNNVE--MAKTNITNLLE 492
            :|::|.|||||||:           ||  .|:.|          |:...|..  :.:.|:.|.:.
  Rat   488 LNLVCFDKTGTLTE-----------DG--LDLWG----------IQRVENTRFLLPEDNVCNEML 529

  Fly   493 IG-------AVCNNAYIQNGTLLGQP-------------TEGALVAVAMKNGMYATAENYVR--- 534
            :.       |.|::.....|.|.|.|             .|......|:.|.:..|.   ||
  Rat   530 VKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWVLEEATEEETALHNRIMPTV---VRPSK 591

  Fly   535 ---------------------------IQEYPFSSEQKMMAVKCIHKYNNNKEEIFFAKGALETL 572
                                       ::::||||..:.|:|  :.:...:|....:.|||.|.:
  Rat   592 QLLPESTTAGDQEMELFELPAIYEIGIVRQFPFSSALQRMSV--VARTLGDKRMDAYMKGAPEVI 654

  Fly   573 LPQCTKYQFGTQTVPLTKQNEAEFLAEAYEIGRKGLRVLALAKGRSMQ----------------- 620
            ...|.     .:|||:    :.|.:.|.|.  ::|.||:|||. |.::
  Rat   655 ASLCK-----PETVPV----DFEKVLEDYT--KQGFRVIALAH-RKLESKLTWHKVQHVSRDAIE 707

  Fly   621 -DLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAI--DPSRRL---QAVPTHA 679
             ::.:.||:.:.:..:......:|.|.::.:|..|||||...||:::  |....|   :.:...|
  Rat   708 NNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDNMLTAVSVARDCGMILPQDKVIIAEA 772

  Fly   680 IPAWPTAGGVPLCSASACCS-TNCLENAMKEIYLTALAQQGLPLVTANLIGIDTI-------HHQ 736
            :|  |..|.|...:.....| |.|.|:       :|:..:.:|:..|:    |::       :|.
  Rat   773 LP--PKDGKVAKINWHYTDSLTQCSES-------SAIDSEAIPIKLAH----DSLEDLQVTRYHF 824

  Fly   737 TLSGQEMDQMNEHQLD---KVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKK 798
            .::|:....:.||..|   |:..:.:||.|::|..|.::|::||.....|||.|||.||..|||:
  Rat   825 AMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLVEALQNVDYFVGMCGDGANDCGALKR 889

  Fly   799 ADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIAL 863
            |..||::.:....|   |:...........:...|.||:...  :.:|..|:.....:.:...::
  Rat   890 AHGGISLSEFEASV---ASPFTSKTPSISCVPNLIREGRAAL--MTSFCVFKFMALYSIIQYFSV 949

  Fly   864 ATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQK-PRNVKQPMITKSVVVNVLLSA 927
            ..|..|.:.|...|.|:|::.:......::.:.|...:::.|: |..:....:..||:..:::|.
  Rat   950 TLLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIVISV 1014

  Fly   928 SIIVLGTLWVFQREMAD--GTLGKTKRDTTMTFTCFVFFDMFNAL---SCRSQTKSVFTIGLTTN 987
            ....||..||.|.:..|  ..:..|.|.     .|:....::|..   ||:.|.....|:...::
  Rat  1015 GFQSLGFFWVKQYKECDPYSEVCNTTRS-----ACWNSSHLYNGTELDSCKIQNYENTTVFFISS 1074

  Fly   988 RMFL-LAVAFS--------------IIGQMLVVY----FPPLQMVFQTEAL-----TPYD--IFF 1026
            ..:| :|||||              .:..::::|    |..|..|...:.|     .||.  |:.
  Rat  1075 FQYLTVAVAFSKGKPFRQPCYKNYFFVISVIILYVFILFIMLHPVASVDQLLEIMCVPYQWRIYM 1139

  Fly  1027 LVSLTSSVLVVSEIKKWFERTMERKMYSTRSE 1058
            |:.:.::..|...::.:|..|:..|:..:|.:
  Rat  1140 LIIVLTNAFVSITVESFFLDTVLWKVVFSRDK 1171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	236/1061 (22%)
		Cation_ATPase_N	112..179	CDD:279080	11/40 (28%)
		E1-E2_ATPase	191..425	CDD:278548	60/266 (23%)
		Cation_ATPase	496..579	CDD:289987	23/125 (18%)
		COG4087	<760..823	CDD:226572	24/62 (39%)
		Cation_ATPase_C	872..1044	CDD:279079	40/203 (20%)
Atp13a3	XP_038944543.1	P-ATPase-V	14..1142	CDD:273738	233/1041 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930