Protein Alignment SPoCk and atp13a2

DIOPT Version :9

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_001073506.1
• Gene: atp13a2 / 568666
• ZFINID: ZDB-GENE-061215-126
• Length: 1170
• Species: Danio rerio
• Alignment Length: 1038
• Identity: 231/1038 - (22%)
• Similarity: 393/1038 - (37%)
• Gaps: 265/1038 - (25%)

  Fly   115 SASEVAGRLQVDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYI----EQFRNPLILLLLGS 175
            :.:::.|:.|     ||...:...|.:|.|.|.:     |...|.|:    |:..||..:.
Zfish   171 TCADLHGQQQ-----GLSRADQSTRKQIFGANII-----DVPVKSYLQLLFEEVLNPFYIF---- 221

  Fly   176 ALVSVIMKQFDDAVSITIAILIVVTVAF-IQEYRSEKSLEELKKLVPPECHCL-------RE-GR 231
            .:.|:|:...|..|.....|.|:..::. :..|.:.|....|:::.     ||       |: |.
Zfish   222 QVFSIILWMSDGYVYYAACIFIISLISIGVSLYETRKQSTTLRRMA-----CLIVNVTVRRDTGE 281

  Fly   232 LDTFLARELVPGDIVHLNV-GDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTNVKD 295
            .:...:.||||||.|.:.. |..:|.|..|. |.:..::||..|||:.|..| |.:..:......
Zfish   282 EECVSSEELVPGDCVVIPAEGLLLPCDAALV-AGECMVNESMLTGESIPVMK-TPLSNSEATYNP 344

  Fly   296 HSNMKNIAFMGT-LVRC---GNGKG---IVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGA 353
            .|..::..|.|| :::.   |.|||   :|..||..:..|::...:...:    ||
Zfish   345 ESQRRHTLFCGTQIIQAKGGGPGKGAIAVVTCTGFLTAKGDLISSILYPQ----PL--------- 396

  Fly   354 QLSFYS-----FLIIGVIMLLGWL--------QGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLA 405
            ...||.     .|.:|::.|:|.:        ...|..|:...|:.:....:|..||..:|....
Zfish   397 DFRFYRDAMKFLLFLGLLALIGTIYSLVILSKSNTPWKELIIRSLDIVTIIVPPALPAAITTATI 461

  Fly   406 LGVMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMADVTGAGYNDQG 470
            ....|:.::.......|.:...|.:::.|.|||||||:..:...      |.| :|||..:   |
Zfish   462 YAQNRLKRQGVFCISPPRINICGKISLFCFDKTGTLTEEGLDVW------GVM-EVTGGVF---G 516

  Fly   471 EIHIRHCNNVEMAKTNITN--------LLEIGAVCNNAYIQNGTLLGQPTE-------------- 513
            |:              :.:        :|...|.|::..:..|..||.|.|
Zfish   517 EL--------------VPDPLFLPPGLMLSALASCHSVALLGGQALGDPLELKMIESTGWELTEP 567

  Fly   514 -----------GALVAVAMK--NGMYATAENYVR-----IQEYPFSSEQKMMAVKCIHKYNNNKE 560
                       |..|...|:  .....|..|.|.     ::.:||||..:.|:|..:..  ....
Zfish   568 ENDMGHDSEFGGHRVLAVMRPPASELLTEGNSVSQPVAIVRRFPFSSSLQRMSVVTVGP--AEPS 630

  Fly   561 EIFFAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFLAEAYEIGRKGLRVLALA----------- 614
            .:.|.|||.|.:...|.|     ::||      :.|.....|...:|.|||.||
Zfish   631 PVAFIKGAPEMVASFCHK-----ESVP------SHFSHTLREYASQGFRVLGLAYKHLAKETDLS 684

  Fly   615 --------KGRSMQDLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRR 671
                    ||.:     :.||:.:.:..:|...|.|:.|..:.:|..|||||  ....|::.:|.
Zfish   685 TVERVEVEKGMN-----FLGLLVMKNQVKPESAEVIQTLTLAQLRPVMVTGD--NILTAVNVARV 742

  Fly   672 LQAVP-------THAIPAWPTAGGVPLC------SASACCST-NCLENAMKEIYLTALAQQGLPL 722
            ...||       .||.|  ||||.....      .|:|..:| ..::..::..|.:|:.
Zfish   743 CGMVPLHEKVIFVHASP--PTAGSQASLQFHEGEGATATINTQQTIDIPVQGQYQSAVG------ 799

  Fly   723 VTANLIGIDTIHHQTLSGQEMDQMNEH---QLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVG 784
                       :|..::|.....:.:|   .|.||....:::.|::|..|.::||:||:....||
Zfish   800 -----------YHLAINGMSFAALCDHFPEYLPKVLMRGTIYARMTPEQKTQLVKALQKLNYRVG 853

  Fly   785 MTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRF 849
            |.|||.||..||:.||:|:::......|   |:.....:|:...:...|:||           |.
Zfish   854 MCGDGANDCGALRAADVGVSLSDAEASV---ASPFTSKSDNISCVPLLIKEG-----------RC 904

  Fly   850 QLSTSIAALALIALATLMDIAN---------PLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQ 905
            .|.||.:....:||.:|:..|:         .|..:|.|:.::::....|..:|.....:|:..|
Zfish   905 SLVTSFSLFKYMALYSLIQFASVLILYTEKTNLGDLQFLFFDLVLVTVLAILMGRGGPSNDLHPQ 969

  Fly   906 KPRN--VKQPMITKSVVVNVLL-----SASIIVLGTLW-VFQREMADGTLGKTKRDTTMTFTCFV 962
            :|..  :..|::...::..|||     |..:|.:...| |.......|.......:.|..|....
Zfish   970 RPAASLLSLPVLASLLMHTVLLILAQVSGLLITMSQDWYVPLNSTRTGAANLPNMEDTSVFAVSG 1034

  Fly   963 FFDMFNALSCRSQTKSVFTIG------LTTNRMFLLAVAF-------------SIIGQMLVVY 1006
            |..:..::        |.|.|      |..|.:|:.|:.|             :||.::|.:|
Zfish  1035 FQYIIMSV--------VITKGFPYKKPLYHNVLFVCALVFLFALMSWLVLFRHTIIHRVLSLY 1089

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	231/1038 (22%)
		Cation_ATPase_N	112..179	CDD:279080	14/67 (21%)
		E1-E2_ATPase	191..425	CDD:278548	58/263 (22%)
		Cation_ATPase	496..579	CDD:289987	24/114 (21%)
		COG4087	<760..823	CDD:226572	22/62 (35%)
		Cation_ATPase_C	872..1044	CDD:279079	32/162 (20%)
atp13a2	NP_001073506.1	P5-ATPase	36..152	CDD:289194
		P-ATPase-V	42..1102	CDD:273738	231/1038 (22%)
		Cation_ATPase_N	<179..229	CDD:279080	15/63 (24%)
		E1-E2_ATPase	241..478	CDD:278548	57/256 (22%)
		Cation_ATPase	<606..646	CDD:289987	11/41 (27%)
		HAD_like	<832..885	CDD:304363	22/55 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573970
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840