Protein Alignment SPoCk and si:dkey-28b4.8

DIOPT Version :10

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: XP_684227.1
• Gene: si:dkey-28b4.8 / 562640
• ZFINID: ZDB-GENE-090501-2
• Length: 1056
• Species: Danio rerio
• Alignment Length: 1058
• Identity: 328/1058 - (31%)
• Similarity: 518/1058 - (48%)
• Gaps: 191/1058 - (18%)

  Fly   113 THSASEVAGRLQVDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNPLILLLLGSAL 177
            |.:..||.|...|:..|||...:.:...:..|.|||........|:..:|||.:.|:.:||.:|.
Zfish     6 TKTVEEVLGYFSVNETTGLSSEQLRKSRERWGPNELPAEEGKSLWELVLEQFEDLLVRILLLAAC 70

  Fly   178 VSVIMKQFDDA-------VSITIAILIVVTVAFI---QEYRSEKSLEELKKLVPPECHCLREGR- 231
            :|..:..|::.       |...:.:||::..|.:   ||..:|.::|.||:..|......|:.|
Zfish    71 ISFTLAWFEEGEGTITAFVEPFVILLILIANAIVGVWQERNAENAIEALKQYEPEMGKVYRQDRK 135

  Fly   232 -LDTFLARELVPGDIVHLNVGDRVPADVRL--FEAVDLSIDESSFTGETEPARKITDVLLNNTNV 293
             :....||::||||||.:.|||:||||:||  ..:..|.:|:|..|||:....|.||.:.:...|
Zfish   136 SVQRVRARDIVPGDIVEVAVGDKVPADIRLTSIRSTTLRVDQSILTGESVSVLKHTDPVPDPRAV 200

  Fly   294 KDHSNMKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFY 358
              :.:.||:.|.||.:..|...|:||:||..:|.|::...|.|.:..:||||:.:|..|.|||
Zfish   201 --NQDKKNMLFSGTNIAAGRAIGVVVATGVHTEIGKIRDEMAATDPERTPLQQKLDQFGEQLS-- 261

  Fly   359 SFLIIGVIMLL----------------GWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALG 407
              ::|.||.:.                .||:|...  .|.|:|:|||||||||||.|:|..||||
Zfish   262 --MVITVICVAVWGINIGHFNDPVHGGSWLRGAVY--YFKIAVALAVAAIPEGLPAVITTCLALG 322

  Fly   408 VMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMAD--------VTGA 464
            ..|||::|:||:.||:||||||.:|||||||||||.|:|:.:.:...|....:        |||:
Zfish   323 TRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRLFIVDMVAGERCLLNEFTVTGS 387

  Fly   465 GYNDQGE-----IHIRHCNNVEMAKTNITNLLEIGAVCNNAYI----QNGTL--LGQPTEGALVA 518
            .|..:||     :.:| |:..|    .:..:..|.|:||::.:    ..|..  :|:.||.||..
Zfish   388 TYAPEGEVSKDGVQVR-CSQYE----GLVEMASICALCNDSSLDYNESKGVFEKVGEATETALCC 447

  Fly   519 VAMKNGMY------------ATA-----ENYVRIQ-EYPFSSEQKMMAVKCIHKYNNNK------ 559
            :..|..::            |||     :..:|.: ...||.::|.|:|.|    :.||
Zfish   448 LVEKMNVFDTDLRGLTSAERATACCSVIKQLMRKELTLEFSRDRKSMSVFC----SPNKLTRSAS 508

  Fly   560 EEIFFAKGALETLLPQC--TKYQFGTQTVPLTKQNEAEFLAEAYE--IGRKGLRVLALAKGRS-- 618
            ....|.|||.|::|.:|  .:...||: |||:.....:.|:...|  .||..||.||:|...|
Zfish   509 GAKMFVKGAPESVLERCRWIRVSGGTR-VPLSSDLREQLLSTVREWGSGRDTLRCLAMATRDSPP 572

  Fly   619 ----------------MQDLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAID 667
                            ..||.:.|.||:.||||..|..::.|..|:|:||.|:|||.:.|||:|
Zfish   573 DPRTLNLENSAAFSEYESDLTFVGCVGMLDPPRKEVLNAVRMCRQAGIRVIMITGDNKGTALSI- 636

  Fly   668 PSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANLIGIDT 732
                                         |.....:....:|     .|:.||
Zfish   637 -----------------------------CRQVGIITEQEEE-----EAEGGL------------ 655

  Fly   733 IHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALK 797
             :...|:|:|.|::..|...:.......|.||.|.||..||:.||...:|..||||||||..|||
Zfish   656 -YGSGLTGREFDELPPHLQRQACRTARCFARVEPTHKSRIVEYLQSLSDITAMTGDGVNDAPALK 719

  Fly   798 KADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIA 862
            ||:|||||| :||.|.|.|::|||.:|:|.||:||:|||:.|:.|::.|:|:.:|::|..:..|.
Zfish   720 KAEIGIAMG-SGTAVAKSASEMILADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIF 783

  Fly   863 LATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMIT-----KSVVVN 922
            |...:.:...|..:|:||:|::.||.||.:||..|.|.|::.:.||:.|:|:|:     :.::|.
Zfish   784 LTAALGMPEALIPVQLLWVNLVTDGFPATALGFNPPDLDIMSRPPRSPKEPLISSWLFCRYLIVG 848

  Fly   923 VLLSASIIVLGTLWVFQR---------------EMADG---------TLGKTKRDTTMTFTCFVF 963
            ..:.|:.:.....|....               :.::|         ::.::....||..:..|.
Zfish   849 CYVGAATVGAAAWWFMAAHDGPKLTFYQLSHYLQCSEGHAEFAGVQCSVFESPYPMTMALSVLVT 913

  Fly   964 FDMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTPYDIFFLV 1028
            .:|.|||:..|:.:|:..:...:|...:.|:..|:....|::|..||.::||...|:......::
Zfish   914 IEMCNALNSLSENQSLLKMPPWSNPWLVGAICLSMALHFLILYVDPLPVIFQIRPLSWPQWVVVL 978

  Fly  1029 SLTSSVLVVSEIKKWFER 1046
            .::..|:::.|..|:..|
Zfish   979 KMSLPVILMDEALKFLAR 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	P-type_ATPase_SPCA	139..1042	CDD:319779	318/1026 (31%)
si:dkey-28b4.8	XP_684227.1	P-type_ATPase_SERCA	5..996	CDD:319778	327/1056 (31%)