Protein Alignment SPoCk and atp1a1

DIOPT Version :9

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_989407.1
• Gene: atp1a1 / 395044
• XenbaseID: XB-GENE-484831
• Length: 1023
• Species: Xenopus tropicalis
• Alignment Length: 1081
• Identity: 301/1081 - (27%)
• Similarity: 482/1081 - (44%)
• Gaps: 186/1081 - (17%)

  Fly    68 KPGKVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEMLLSTSESSTHSASEVAGRLQVDVRTGLK 132
            |.||..|    |:.||                |..|:   |.|....|..|:..:...|::.||.
 Frog    23 KKGKGKD----KDMDE----------------LKKEL---TMEDHKLSLDELHRKFGTDMQRGLS 64

  Fly   133 WTEAKYRAKII---GHNELLLVAEDPTWKKYIEQFRNPLILLLLGSALVSVIMKQFDDA------ 188
            ...|   |:|:   |.|.|......|.|.|:..|......:||...|::..:......|
 Frog    65 TARA---AEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGITAATEEEPT 126

  Fly   189 -----VSITIAILIVVT--VAFIQEYRSEKSLEELKKLVPPECHCLREGRLDTFLARELVPGDIV 246
                 :.:.::.::::|  .::.||.:|.|.:|..|.:||.:...:|.|...:..|.::|.||:|
 Frog   127 NDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKLSINAEDVVLGDLV 191

  Fly   247 HLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTNVKDHSNMKNIAFMGTLVRC 311
            .:..|||:|||||:..|....:|.||.|||:||..:..|  ..|.|..:   .:||||..|....
 Frog   192 EVKGGDRIPADVRIISAHGCKVDNSSLTGESEPQTRSPD--FTNENPLE---TRNIAFFSTNCVE 251

  Fly   312 GNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMD-----ILGAQLSF-YSFLIIGVIMLLG 370
            |..:|:||:||:|:..|.:..:....|..:||:...::     |.|..:.. .||.|:.:|:...
 Frog   252 GTARGVVVNTGDRTVMGRIATLASGLEGGRTPIAIEIEHFIHIITGVAVFLGVSFFILSLILQYT 316

  Fly   371 WLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGCVNVICS 435
            ||      |.....:.:.||.:||||...|||.|.|...|||::|.:||.|..|||||..:.|||
 Frog   317 WL------EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICS 375

  Fly   436 DKTGTLTKNEMT-ATIIITSDGYMADVTGAGYNDQGEIHIRHCNNVEMAKTNITNLLEIGAVCNN 499
            |||||||:|.|| |.:...:..:.||.|   .|..|.       :.:.:....|.|..:..:||.
 Frog   376 DKTGTLTQNRMTVAHMWFDNQIHEADTT---ENQSGA-------SFDKSSPTWTALSRVAGLCNR 430

  Fly   500 AYIQNG---------TLLGQPTEGALV-AVAMKNG-MYATAENYVRIQEYPFSSEQKMMAVKCIH 553
            |..|.|         .:.|..:|.||: .:.:..| :....|...::.|.||:|..|...  .:|
 Frog   431 AVFQAGQENTPILKRDVAGDASESALLKCIELCCGSVRDMREKNPKVAEIPFNSTNKYQL--SVH 493

  Fly   554 KYNNNKEE--IFFAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFLAEAYEIGRKGLRV-----L 611
            |..|..|.  |...|||.|.:|.:|:......:..||.::.:..|.....|:|..|.||     |
 Frog   494 KNANPSESRYILVMKGAPERILDRCSTIVLQGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHL 558

  Fly   612 ALAKGR--------------SMQDLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQET 662
            ||:..:              ..::|.:.||:.:.||||..|.:::.....:|::|.|||||
 Frog   559 ALSDDQFPDGFQFDTEEVNFPTENLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGD---- 619

  Fly   663 ALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANL 727
                           |.|.|...|.||.:.|..        ...:::|    .|:..:|:   |.
 Frog   620 ---------------HPITAKAIAKGVGIISEG--------NETVEDI----AARLNIPV---NQ 654

  Fly   728 IGIDTIHHQTLSGQEMDQMNEHQLDKVANNVS--VFYRVSPRHKLEIVKSLQRSGNIVGMTGDGV 790
            :.........:.|.::..|.:.|:|.:..:.:  ||.|.||:.||.||:..||.|.||.:|||||
 Frog   655 VNPRDAKACVIHGSDLKDMAQEQIDDILKHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGV 719

  Fly   791 NDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSI 855
            ||..||||||||||||..|:||.|:||||||::|:|.:|:..:|||:.||.|::..:.:.|:::|
 Frog   720 NDSPALKKADIGIAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNI 784

  Fly   856 AALALIALATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMITKSVV 920
            ..:....:..:.:|..||..:.||.|::..|..||.||..|..:.|::|::|||.|...:....:
 Frog   785 PEITPFLIFIVANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERL 849

  Fly   921 VN-------------------VLLSASIIVLGTL----------WVFQREMADGTLGKTKRDTTM 956
            ::                   |:|:.:..:..||          |....|.:.|.....::...:
 Frog   850 ISMAYGQIGMIQALGGFFTYFVILAENGFLPWTLLGIRVNWDDRWNNDVEDSYGQQWTYEQRKIV 914

  Fly   957 TFTCFVFF-------DMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVF 1014
            .|||...|       ...:.:.|:::..|||..|: .|::.:..:.........:.|.|.:.:..
 Frog   915 EFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGM-KNKILIFGLFEETALAAFLSYCPGMDVAL 978

  Fly  1015 QTEALTPYDIFFLVSLTSSVLVVSEIKK---------WFER 1046
            :...|.|...|.....:..:.:..|::|         |.|:
 Frog   979 RMYPLKPTWWFCAFPYSLLIFIYDEVRKLIIRRSPGGWVEK 1019

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	291/1039 (28%)
		Cation_ATPase_N	112..179	CDD:279080	18/69 (26%)
		E1-E2_ATPase	191..425	CDD:278548	79/241 (33%)
		Cation_ATPase	496..579	CDD:289987	27/95 (28%)
		COG4087	<760..823	CDD:226572	43/62 (69%)
		Cation_ATPase_C	872..1044	CDD:279079	41/216 (19%)
atp1a1	NP_989407.1	ATPase-IIC_X-K	32..1023	CDD:273445	296/1068 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100699at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010