Protein Alignment SPoCk and atp2b1a

DIOPT Version :10

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: XP_009298531.1
• Gene: atp2b1a / 378746
• ZFINID: ZDB-GENE-030925-29
• Length: 1257
• Species: Danio rerio
• Alignment Length: 973
• Identity: 259/973 - (26%)
• Similarity: 425/973 - (43%)
• Gaps: 248/973 - (25%)

  Fly   187 DAVSITIAILIVVTVAFIQEYRSEKSLEELKKLVPPE--CHCLREGRLDTFLARELVPGDIVHLN 249
            :..:|.::::.||.|....::..||....|:..:..|  ...:|.|::......|:|.|||..:.
Zfish   150 EGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFSVVRGGQVIQIHVAEIVVGDIAQIK 214

  Fly   250 VGDRVPADVRLFEAVDLSIDESSFTGETEPARKITD---VLLNNTNVKDHSNMKNIAFMGTLVRC 311
            .||.:|||..|.:..||.|||||.|||::..:|..|   :||:.|:|.:
Zfish   215 YGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDAMLLSGTHVME---------------- 263

  Fly   312 GNGKGIVVSTGERSEFGEVFKMMQA---------------------------------------- 336
            |:||.:|.:.|..|:.|.:|.::.|
Zfish   264 GSGKIVVTAVGVNSQTGIIFTLLGAGEDDDDEEEKEKKKEKERKKEKKNKKQDGSVENRKKAKAQ 328

  Fly   337 ------------------EEAPKTPL-QKSMDIL--------------GAQLSFYSFLIIGVIML 368
                              ||..|..| :|...:|              |..:|..:.:|:.|:.:
Zfish   329 DGAAMEMQPLNSDEGADGEEKRKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVVLFV 393

  Fly   369 LG--WLQGKP------------LSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVK 419
            :.  |:...|            ..:.|.|.|::.|.|:|||||:.||::||..|.:|.|.|::|:
Zfish   394 VDTFWVDKIPWDSGCIPIYIQFFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVR 458

  Fly   420 KLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMADVTGAGYNDQGEIHIRHCNNVEMAK 484
            .|...||:|....||||||||||.|.||...:..:|.                |.|.....::..
Zfish   459 HLDACETMGNATAICSDKTGTLTMNRMTVVQVFIADK----------------HYRKVPEPDVVP 507

  Fly   485 TNITNLLEIGAVCNNAYI-------QNGTL---LGQPTEGALVAVAM---KNGMYATAENYVRIQ 536
            .:..:||.:|...|.||.       :.|.|   :|..||.||:..|:   |:  |....|.:..:
Zfish   508 ASTMDLLIVGISVNCAYTTKIMSPEKEGGLNRQVGNKTECALLGFALDLKKD--YQAVRNEIPEE 570

  Fly   537 E----YPFSSEQKMMAVKCIHKYNNNKEEIFFAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFL 597
            :    |.|:|.:|.|:.  :.| |::.....|:|||.|.||.:|.|....|....:.:..:.:.:
Zfish   571 KLYKVYTFNSVRKSMST--VLK-NDDGSYRMFSKGASEILLKKCFKILTSTGEAKVFRPRDRDDM 632

  Fly   598 AEAY--EIGRKGLRVLALA-------KGRSMQD--------LIYCGLVGITDPPRPLVRESIEML 645
            .:..  .:..:|||.:.||       :|....|        |....:|||.||.||.|.::|...
Zfish   633 VKRVIEPMASEGLRTICLAYRDFPASEGEPDWDNEADILTRLTCVCVVGIEDPVRPEVPDAIRKC 697

  Fly   646 MQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEI 710
            .::|:.|:|||||...||.||                                :|.|
Zfish   698 QRAGITVRMVTGDNLNTARAI--------------------------------ATKC-------- 722

  Fly   711 YLTALAQQGLPLVTANLIGIDTIHHQTLSGQEMD--------QMNEHQLDKVANNVSVFYRVSPR 767
               .:.|          :|.|.:   .|.|:|.:        ::.:.::||:...:.|..|.||.
Zfish   723 ---GILQ----------VGDDFL---CLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPT 771

  Fly   768 HKLEIVKSL-------QRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDD 825
            .|..:||.:       ||  .:|.:||||.|||.||||||:|.|||..||||.|||:|:||.:|:
Zfish   772 DKHTLVKGIIDSTVVEQR--QVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDN 834

  Fly   826 FHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPA 890
            |.:|:.|:..|:.::.:|..|::|||:.::.|:.:......:...:||.|:|:||:|:|||...:
Zfish   835 FSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLAS 899

  Fly   891 QSLGVEPVDHDVLKQKPRNVKQPMITKSVVVNVLLSA--SIIVLGTLWVFQREMADGTLGK---- 949
            .:|..||....:|.:||....:|:|:::::.|:|..|  .:|::.||.....:|.:...|:
Zfish   900 LALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAVYQLIIIFTLLFAGEKMFNIDSGRYADL 964

  Fly   950 ---TKRDTTMTFTCFVFFDMFNALSCRS--QTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYF 1007
               .....|:.|..||...:||.::.|.  ..::||. |:..|.:|...|..:.:.|:::|.|
Zfish   965 HAPPSEHYTIVFNTFVMMQLFNEINARKIHGERNVFE-GIFNNMIFCTIVFGTFVIQIVIVQF 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	P-type_ATPase_SPCA	139..1042	CDD:319779	259/973 (27%)
atp2b1a	XP_009298531.1	ATPase-IIB_Ca	10..1064	CDD:273668	259/973 (27%)
		ATP_Ca_trans_C	1105..1182	CDD:463575