Protein Alignment SPoCk and atp2a1

DIOPT Version :9

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_001007030.1
• Gene: atp2a1 / 260440
• ZFINID: ZDB-GENE-020905-1
• Length: 994
• Species: Danio rerio
• Alignment Length: 1073
• Identity: 329/1073 - (30%)
• Similarity: 515/1073 - (47%)
• Gaps: 219/1073 - (20%)

  Fly   101 TPEML--LSTSESSTHSASEVAGRLQVDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQ 163
            |||.|  ...|||:..:..:|            |..:|||     |.|||........|:..:||
Zfish     9 TPECLAYFGVSESTGLTPEQV------------KKNQAKY-----GFNELPAEEGKSIWELVVEQ 56

  Fly   164 FRNPLILLLLGSALVSVIMKQFDDA-------VSITIAILIVVTVAFI---QEYRSEKSLEELKK 218
            |.:.|:.:||.:|.:|.::..|::.       |...:.:||::..|.:   ||..:|.::|.||:
Zfish    57 FEDLLVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAVVGVWQERNAESAIEALKE 121

  Fly   219 LVPPECHCLREGR--LDTFLARELVPGDIVHLNVGDRVPADVRL--FEAVDLSIDESSFTGETEP 279
            ..|......|..|  :....|||:||||||.::|||:||||:|:  ..:..|.:|:|..|||:
Zfish   122 YEPEMGKVYRSDRKSVQRIKAREIVPGDIVEVSVGDKVPADIRITAIRSTTLRVDQSILTGES-- 184

  Fly   280 ARKITDVLLNNTNVKD----HSNMKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAP 340
                ..|:.:..:|.|    :.:.||:.|.||.:..|...|:||:||..:|.|::...|.|.|..
Zfish   185 ----VSVIKHTESVPDPRAVNQDKKNMLFSGTNIAAGKAIGVVVATGVSTEIGKIRDQMAATEQE 245

  Fly   341 KTPLQKSMDILGAQLSFYSFLIIGVIMLL------------GWLQGKPLSEMFNISVSLAVAAIP 393
            |||||:.:|..|.|||....||...:.|:            .|::|...  .|.|:|:|||||||
Zfish   246 KTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAVY--YFKIAVALAVAAIP 308

  Fly   394 EGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATII------- 451
            ||||.|:|..||||..||||:|:||:.||:||||||.:|||||||||||.|:|..|.:
Zfish   309 EGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMCVTKMFVIEKVE 373

  Fly   452 ---ITSDGYMADVTGAGYNDQGEIHIR----HCNNVEMAKTNITNLLEIGAVCNNA---YIQNGT 506
               :|.|.|  |::|:.|..:||:...    .|...:    .:..|..|.|:||::   |.::..
Zfish   374 GESVTLDQY--DISGSKYTPEGEVTKNGLPVKCGQFD----GLVELATICALCNDSSLDYNESKG 432

  Fly   507 L---LGQPTEGALVAVAMKNGMYAT-AENYVRIQE-----------------YPFSSEQKMMAVK 550
            :   :|:.||.||..:..|..::.| .....:::.                 ..||.::|.|:|.
Zfish   433 IYEKVGEATETALCCLVEKMNVFNTDVRGLSKVERANTCCAVIKQLMKKDFTLEFSRDRKSMSVY 497

  Fly   551 CIHKYNNNKEEI---FFAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFLA--EAYEIGRKGLRV 610
            | .....:|..:   .|.|||.|.::.:|...:.||..||||...:.:.:|  :.:..||..||.
Zfish   498 C-SPAKASKAPVGNKMFVKGAPEGVIDRCAYVRVGTTRVPLTGPVKDKIMAVIKEWGTGRDTLRC 561

  Fly   611 LALA------KGRSMQ------------DLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTG 657
            ||||      :...|.            ||.:.|.||:.||||..|..|||:...:|:||.|:||
Zfish   562 LALATRDNPLRPEEMNLEDSTKFAEYETDLTFVGCVGMLDPPRKEVVGSIELCRAAGIRVIMITG 626

  Fly   658 DAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPL 722
            |.:.||:||  .||
Zfish   627 DNKGTAVAI--CRR--------------------------------------------------- 638

  Fly   723 VTANLIGI----DTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIV 783
                 |||    :.:..:..:|:|.|.:...|..:.......:.||.|.||.:||:.||....|.
Zfish   639 -----IGIFSDDEDVTGRAFTGREFDDLPLPQQREAVRKACCYARVEPSHKSKIVEFLQGFDEIT 698

  Fly   784 GMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVR 848
            .||||||||..|||||:|||||| :||.|.|.|::|:|.:|:|.:|:||:|||:.|:.|::.|:|
Zfish   699 AMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSASEMVLADDNFSSIVAAVEEGRAIYNNMKQFIR 762

  Fly   849 FQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQP 913
            :.:|:::..:..|.|...:.:...|..:|:||:|::.||.||.:||..|.|.|::.:.||:.|:|
Zfish   763 YLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKAPRSPKEP 827

  Fly   914 MIT-----KSVVVNVLLSASIIVLGTLWV----------------FQREMADG--------TLGK 949
            :|:     :.:.:...:.|:.:.....|.                |.:..||.        .:.:
Zfish   828 LISGWLFFRYLAIGGYVGAATVAAAGWWFLYCDEGPMVSFYQLSHFMQCTADNEDFAGIECEVFE 892

  Fly   950 TKRDTTMTFTCFVFFDMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVF 1014
            .....||..:..|..:|.|||:..|:.:|:..:...:|.....|:..|:....:::|..||.|:|
Zfish   893 AAPPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWSNLWLAGAMTLSMSLHFMIIYVDPLPMIF 957

  Fly  1015 QTEALTPYDIFFLV-SLTSSVLVVSEIKKWFER 1046
            :...|. :|.:.:| .|:..|:::.|..|:..|
Zfish   958 KLTHLN-FDQWIVVLKLSFPVILIDEALKFVAR 989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	324/1062 (31%)
		Cation_ATPase_N	112..179	CDD:279080	17/66 (26%)
		E1-E2_ATPase	191..425	CDD:278548	98/256 (38%)
		Cation_ATPase	496..579	CDD:289987	23/109 (21%)
		COG4087	<760..823	CDD:226572	36/62 (58%)
		Cation_ATPase_C	872..1044	CDD:279079	48/201 (24%)
atp2a1	NP_001007030.1	Cation_ATPase_N	4..72	CDD:279080	24/79 (30%)
		ATPase-IIA1_Ca	53..989	CDD:273452	311/1010 (31%)
		E1-E2_ATPase	93..340	CDD:278548	98/254 (39%)
		Cation_ATPase	419..528	CDD:289987	23/109 (21%)
		HAD	<604..712	CDD:289480	44/165 (27%)
		Cation_ATPase_C	784..987	CDD:279079	48/203 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	1	1.010	-	-		D100699at2759
OrthoFinder	1	1.000	-	-		FOG0000231
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100158
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.760