Protein Alignment SPoCk and Atp2a3

DIOPT Version :10

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: XP_063124535.1
• Gene: Atp2a3 / 25391
• RGDID: 2175
• Length: 1189
• Species: Rattus norvegicus
• Alignment Length: 1056
• Identity: 328/1056 - (31%)
• Similarity: 522/1056 - (49%)
• Gaps: 182/1056 - (17%)

  Fly   107 STSESSTHSASEVAGRLQVDVRTGL---KWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNPL 168
            |..|:...||::|..|..|....||   :.|:|:.|   .|.|||........|:..:|||.:.|
  Rat   190 SMEEAHLLSAADVLRRFSVTAEGGLTLEQVTDARER---YGPNELPTEEGKSLWELVVEQFEDLL 251

  Fly   169 ILLLLGSALVSVIMKQFDDAVSITIA-------ILIVVTVAFI---QEYRSEKSLEELKKLVPPE 223
            :.:||.:||||.::..|::....|.|       :||:|..|.:   ||..:|.::|.||:..|..
  Rat   252 VRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 316

  Fly   224 CHCLREGR--LDTFLARELVPGDIVHLNVGDRVPADVRLFE--AVDLSIDESSFTGETEPARKIT 284
            ...:|..|  :....||::||||||.:.|||:||||:||.|  :..|.:|:|..|||:....|.|
  Rat   317 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHT 381

  Fly   285 DVLLNNTNVKDHSNMKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMD 349
            |.:.:...|  :.:.||:.|.||.:..|...|:.|:||..:|.|::...|.|.|..:||||:.:|
  Rat   382 DAIPDPRAV--NQDKKNMLFSGTNIASGKALGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLD 444

  Fly   350 ILGAQLSFYSFLIIGVIMLL------------GWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTV 402
            ..|.|||....:|...:.::            .||:|...  .|.|:|:|||||||||||.|:|.
  Rat   445 EFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVY--YFKIAVALAVAAIPEGLPAVITT 507

  Fly   403 TLALGVMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTAT---IIITSDG-----YMA 459
            .||||..|||::|:||:.||:||||||.:|||||||||||.|:|:..   ::..::.     :..
  Rat   508 CLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAEAGACRLHEF 572

  Fly   460 DVTGAGYNDQGEI----HIRHCNNVEMAKTNITNLLEIGAVCNNAYIQNGTL------LGQPTEG 514
            .::|..|..:||:    .:..|...:    .:..|..|.|:||::.:.....      :|:.||.
  Rat   573 TISGTTYTPEGEVRQGEQLVRCGQFD----GLVELATICALCNDSALDYNEAKGVYEKVGEATET 633

  Fly   515 ALVAVAMKNGMYAT-AENYVRIQE-----------------YPFSSEQKMMAVKCIHKYNNNKEE 561
            ||..:..|..::.| .:...|::.                 ..||.::|.|:|.|.....:.|.:
  Rat   634 ALTCLVEKMNVFDTDLKGLSRVERAGACNSVIKQLMRKEFTLEFSRDRKSMSVYCTPTRADPKAQ 698

  Fly   562 --IFFAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFLAEA--YEIGRKGLRVLALA------KG 616
              ..|.|||.|:::.:|:..:.|::||||:..:....||:.  :..|...||.||||      :.
  Rat   699 GSKMFVKGAPESVIERCSSVRVGSRTVPLSATSREHILAKIRDWGSGSDTLRCLALATRDTPPRK 763

  Fly   617 RSMQ------------DLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPS 669
            ..||            .|.:.|.||:.|||||.|...|....::|:||.|:|||.:.||:||  .
  Rat   764 EDMQLDDCSQFVQYETGLTFVGCVGMLDPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAI--C 826

  Fly   670 RRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANLIGIDTIH 734
            |||                                              |:...|.:::|
  Rat   827 RRL----------------------------------------------GIFGDTEDVLG----- 840

  Fly   735 HQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKA 799
             :..:|:|.|.::..|..:.......|.||.|.||..||::||....|..||||||||..|||||
  Rat   841 -KAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 904

  Fly   800 DIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALA 864
            :|||||| :||.|.|.||:|:|.:|:|.:|:||:|||:.|:.|::.|:|:.:|:::..:..|.|.
  Rat   905 EIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLT 968

  Fly   865 TLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMIT-----KSVVVNVL 924
            .::.:...|..:|:||:|::.||.||.:||..|.|.|::::.|||.::.:|:     :.:.:.|.
  Rat   969 AILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPREALISGWLFFRYLAIGVY 1033

  Fly   925 LSASIIVLGTLWV----------------FQREMADGTL--------GKTKRDTTMTFTCFVFFD 965
            :..:.:...|.|.                |.:...|..|        .:::..|||..:..|..:
  Rat  1034 VGLATVAAATWWFLYDAEGPQVTFHQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSVLVTIE 1098

  Fly   966 MFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTPYDIFFLVSL 1030
            |.|||:..|:.:|:..:....|...|.||..|:....|::..|||.::||...|:......::.:
  Rat  1099 MCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHFLILLVPPLPLIFQVTPLSGRQWGVVLQM 1163

  Fly  1031 TSSVLVVSEIKKWFER 1046
            :..|:::.|..|:..|
  Rat  1164 SLPVILLDEALKYLSR 1179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	P-type_ATPase_SPCA	139..1042	CDD:319779	315/1015 (31%)
Atp2a3	XP_063124535.1	None