Protein Alignment SPoCk and atp1a1a.5

DIOPT Version :9

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_835200.1
• Gene: atp1a1a.5 / 245703
• ZFINID: ZDB-GENE-020501-1
• Length: 1023
• Species: Danio rerio
• Alignment Length: 1113
• Identity: 314/1113 - (28%)
• Similarity: 490/1113 - (44%)
• Gaps: 224/1113 - (20%)

  Fly    58 KDSRAVPQNVKPGKVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEMLLSTSESSTHSASEVAGR 122
            :|....|:..|..| .||.:.|:  |..:|...         ||.|              |::.:
Zfish    17 EDGVKTPKKGKKNK-KDMDELKK--EVEMDDHK---------LTME--------------ELSRK 55

  Fly   123 LQVDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQ-FRNPLILLLLGS-------ALVS 179
            ...|:..||..:.|.......|.|.|......|.|.::..| |.....||.:|:       ::.:
Zfish    56 YGTDLTKGLPVSRAMEVLMRDGPNALTPPVITPEWVRFCRQLFGGFQTLLWIGAFLCYFAFSIQA 120

  Fly   180 VIMKQFDDAVSITIAILIVVTV----AFIQEYRSEKSLEELKKLVPPECHCLREGRLDTFLAREL 240
            ...:..:|.:.:.|.:..||||    ::.||.:|.:.::..|.|||.:...:|:|......|.|:
Zfish   121 ATEEPVNDNLYLGIVLTFVVTVNGCFSYSQEAKSCRIMDSFKNLVPQKALVVRDGEKKIIDAEEV 185

  Fly   241 VPGDIVHLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTNVKDHSNMKNIAFM 305
            |.||:|.:..||::|||:|:..:....:|.||.|||:||..:..|:...|.     ...:||||.
Zfish   186 VVGDLVEVKGGDKIPADIRIVSSHGCKVDNSSLTGESEPQIRTPDMSSENP-----LETRNIAFF 245

  Fly   306 GTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMD-----ILGAQLSF-YSFLIIG 364
            .|....|..:||||:||:|:..|.:..:....|..:|||.:.::     |.|..:.. .:||||.
Zfish   246 STNCIDGAARGIVVNTGDRTVMGRIASLASNLEGGQTPLGREIEHFIHIITGVAVFLGTTFLIIS 310

  Fly   365 VIMLLGWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGC 429
            |::...||:|      ....:.|.||.:|||||..|||.|.|....|||:|.:||.|..|||||.
Zfish   311 VMLGFTWLEG------IIFLIGLIVANVPEGLPCTVTVALTLTAKHMAKKNCLVKNLEAVETLGS 369

  Fly   430 VNVICSDKTGTLTKNEMT-ATIIITSDGYMADV----TGAGYNDQGEIHIRHCNNVEMAKTNITN 489
            .:.||||||||||:|.|| |.:...:..::||.    |||.:              :.:....:.
Zfish   370 TSTICSDKTGTLTQNRMTVAHMWFDNQIHIADTTENQTGASF--------------DRSSATWSA 420

  Fly   490 LLEIGAVCNNAYIQNG---------TLLGQPTEGAL-----VAVAMKNGMYATAENYVRIQEYPF 540
            |..:..:||.|..|:.         ...|..:|.||     :......||   .|||.::.|.||
Zfish   421 LARVAGLCNRAVFQSNQSHLPVLRRETAGDASESALLKCIELCCGSVTGM---RENYPKVAEIPF 482

  Fly   541 SSEQKMMAVKCIHKYNNNKE--EIFFAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFLAEAYEI 603
            :|..|...  .||:..|:.|  .:...|||.|.:|.:|:......:..||..:.:.:|.....::
Zfish   483 NSISKYQL--SIHENPNSSEPKHLLVMKGAPERILDRCSTILIEGKEHPLDDEMKEDFQNAYVQL 545

  Fly   604 GRKGLRVLALA----------KGRSM---------QDLIYCGLVGITDPPRPLVRESIEMLMQSG 649
            |..|.|||...          :|.:.         ::|.:.||:.:.||||..|.:::.....:|
Zfish   546 GGLGERVLGFCHFCLPDDQFPEGFAFDTEEMNFPTENLCFVGLMSMIDPPRAAVPDAVAKCRSAG 610

  Fly   650 VRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTA 714
            ::|.|||||                   |.|.|...|.||.:.|.
Zfish   611 IKVIMVTGD-------------------HPITAKAIAKGVGIISE-------------------- 636

  Fly   715 LAQQGLPLVTANL-IGIDTIHHQ-----TLSGQEMDQMNEHQLDKVANNVS--VFYRVSPRHKLE 771
             ..:.:..:.|.| |.||.::.:     .:.|.|:..|.:.|||.|..:.:  ||.|.||:.||.
Zfish   637 -GNETVDDIAARLKIHIDEVNPRDAKACVIHGGELKNMTDEQLDDVLQHHTEIVFARTSPQQKLI 700

  Fly   772 IVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEG 836
            ||:..||.|.||.:|||||||..||||||||:|||..|:||.|:||||||::|:|.:|:..:|||
Zfish   701 IVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEG 765

  Fly   837 KGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHD 901
            :.||.|::..:.:.|||.|..::...:..|..|..||..:.||.|::..|..||.|...|..:.|
Zfish   766 RLIFDNLKKSICYTLSTKIPEMSPFLMFVLAGIPLPLGTVTILCIDLGTDMVPAISFAYENAESD 830

  Fly   902 VLKQKPRNVKQPMITKSVVVNV------LLSA------SIIVL---------------------- 932
            ::|::|||.....:....:|:|      :::|      ..::|
Zfish   831 IMKRQPRNAATDRLVNERLVSVSYGQIGVMNAFGGFFTYFVILAENGFLPWDLVGLRIGWNDRYF 895

  Fly   933 -------GTLWVF-QREMADGTLGKTKRDTTMTFTCFVFFDMFNALSCRSQTKSVFTIGLTTNRM 989
                   |..|.: ||::.:.|.      .|..||..|.......|.|:|:..|:...|: .||:
Zfish   896 SEVEDSYGQQWTYEQRKVLEYTC------HTAYFTSIVIMQWTTLLVCKSRRLSLAKQGM-KNRV 953

  Fly   990 FLLAVAFSIIGQMLVV----YFPPLQMVFQTEALTPYDIFFLVSLTSSVLVVSEIKKWFERT--- 1047
                :.||:..:..:.    |.|.:.:..:...|.|...|........:.:..|::|.|.|.
Zfish   954 ----LTFSLFEETAIAAFLSYCPGMDIAVRMYPLKPMWWFCAFPYMILIFIYDEVRKHFIRQNPG 1014

  Fly  1048 --MERKMY 1053
              :||:.|
Zfish  1015 GWVERETY 1022

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	299/1055 (28%)
		Cation_ATPase_N	112..179	CDD:279080	15/74 (20%)
		E1-E2_ATPase	191..425	CDD:278548	84/243 (35%)
		Cation_ATPase	496..579	CDD:289987	28/98 (29%)
		COG4087	<760..823	CDD:226572	42/62 (68%)
		Cation_ATPase_C	872..1044	CDD:279079	44/217 (20%)
atp1a1a.5	NP_835200.1	ATPase-IIC_X-K	32..1023	CDD:273445	310/1097 (28%)
		Cation_ATPase_N	41..115	CDD:214842	19/96 (20%)
		E1-E2_ATPase	134..365	CDD:278548	84/241 (35%)
		Cation_ATPase	427..521	CDD:289987	28/98 (29%)
		COG4087	603..752	CDD:226572	68/188 (36%)
		Cation_ATPase_C	799..1008	CDD:279079	44/219 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920