Protein Alignment SPoCk and Atp2c1

DIOPT Version :10

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_001240760.1
• Gene: Atp2c1 / 235574
• MGIID: 1889008
• Length: 952
• Species: Mus musculus
• Alignment Length: 1004
• Identity: 579/1004 - (57%)
• Similarity: 720/1004 - (71%)
• Gaps: 92/1004 - (9%)

  Fly    51 QRTISHVKDSRAVPQNVKPGKVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEMLLSTSESSTHS 115
            ::.:|.::..||..|..:..|:           .||:.:         |:.|  :|::..:|..:
Mouse    22 RKYLSTLRSQRAEEQVARFQKI-----------PNVENE---------TMIP--VLTSKRASELA 64

  Fly   116 ASEVAGRLQVDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNPLILLLLGSALVSV 180
            .|||||.||.|::.||..:|..:|....|.||..:..::|.|||||.||:||||:|||.||::|:
Mouse    65 VSEVAGLLQADLQNGLNKSEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISI 129

  Fly   181 IMKQFDDAVSITIAILIVVTVAFIQEYRSEKSLEELKKLVPPECHCLREGRLDTFLARELVPGDI 245
            :|:|||||||||:||:|||||||:||||||||||||.|||||||||:|||:|:..|||:|||||.
Mouse   130 LMRQFDDAVSITVAIVIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDT 194

  Fly   246 VHLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKIT--DVLLNNTNVKDHSNMKNIAFMGTL 308
            |.|:||||||||:|||||||||:||||.||||.|..|:|  ....|.    |.::..||||||||
Mouse   195 VCLSVGDRVPADLRLFEAVDLSVDESSLTGETAPCSKVTAPQPAANG----DLASRSNIAFMGTL 255

  Fly   309 VRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVIMLLGWLQ 373
            ||||..||||:.|||.|||||||||||||||||||||||||:||.|||||||.|||:|||:|||.
Mouse   256 VRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLL 320

  Fly   374 GKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGCVNVICSDKT 438
            ||.:.|||.|||||||||||||||||||||||||||||.|:.:||||||.||||||.||||||||
Mouse   321 GKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKT 385

  Fly   439 GTLTKNEMTATIIITSDGYMADVTGAGYNDQGEIHIRHCNNVEMAKTN--ITNLLEIGAVCNNAY 501
            |||||||||.|.|:||||..|:|||.|||..||:.:.  .:|.....|  ::.::|.|.|||:|.
Mouse   386 GTLTKNEMTVTHILTSDGLHAEVTGVGYNQFGEVIVD--GDVVHGFYNPAVSRIVEAGCVCNDAV 448

  Fly   502 IQNGTLLGQPTEGALVAVAMKNGMYATAENYVRIQEYPFSSEQKMMAVKCIHKYNNNKEEIFFAK 566
            |:|.||:|:||||||:|:|||.|:....::|:|..|||||||||.|||||:|:...::.||.|.|
Mouse   449 IRNNTLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 513

  Fly   567 GALETLLPQCTKYQFGTQTVPLTKQNEAEFLAEAYEIGRKGLRVLALAKGRSMQDLIYCGLVGIT 631
            ||.|.::..||.|....||:.||:|....:..|...:|..||||||||.|..:..|.:.|||||.
Mouse   514 GAYEQVIKYCTTYNSKGQTLALTQQQRDLYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGII 578

  Fly   632 DPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASA 696
            ||||..|:|::..|:.|||.:||:|||:||||:||
Mouse   579 DPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAI------------------------------ 613

  Fly   697 CCSTNCLENAMKEIYLTALAQQGLPLVTANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVF 761
                                        |:.:|:.:...|::||:|:|.|....|.::...|:||
Mouse   614 ----------------------------ASRLGLYSKTSQSVSGEEVDTMEVQHLSQIVPKVAVF 650

  Fly   762 YRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDF 826
            ||.|||||::|:||||::|.:|.||||||||.||||.||||:|||:.||||||||||||||:|||
Mouse   651 YRASPRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDF 715

  Fly   827 HTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPAQ 891
            .||::||||||||:.||:||||||||||||||.||:|||||:..|||||||||||||||||||||
Mouse   716 QTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQ 780

  Fly   892 SLGVEPVDHDVLKQKPRNVKQPMITKSVVVNVLLSASIIVLGTLWVFQREMADGTLGKTKRDTTM 956
            ||||||||.||:::.|||.|..::||::::.:|:|:.|||.|||:||.||:.|..:  |.|||||
Mouse   781 SLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVI--TPRDTTM 843

  Fly   957 TFTCFVFFDMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTP 1021
            |||||||||||||||.||||||||.|||.:|:||..||..||:||:||:||||||.|||||:|:.
Mouse   844 TFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSI 908

  Fly  1022 YDIFFLVSLTSSVLVVSEIKKWFERTMER 1050
            .|:.||:.|||||.:||||.|..||:.|:
Mouse   909 LDLLFLLGLTSSVCIVSEIIKKVERSREK 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	P-type_ATPase_SPCA	139..1042	CDD:319779	553/906 (61%)
Atp2c1	NP_001240760.1	P-type_ATPase_SPCA	88..929	CDD:319779	553/906 (61%)