Protein Alignment SPoCk and atp2a2

DIOPT Version :9

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: XP_031748548.1
• Gene: atp2a2 / 100489059
• XenbaseID: XB-GENE-1012933
• Length: 1083
• Species: Xenopus tropicalis
• Alignment Length: 1057
• Identity: 332/1057 - (31%)
• Similarity: 514/1057 - (48%)
• Gaps: 189/1057 - (17%)

  Fly   113 THSASEVAGRLQVDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNPLILLLLGSAL 177
            |.:..||.....|:..|||...:.|.:.:..|.|||........|:..||||.:.|:.:||.:|.
 Frog     6 TKTVEEVLAHFNVNESTGLSLEQVKKQKERWGANELPAEEGKTLWELVIEQFEDLLVRILLLAAC 70

  Fly   178 VSVIMKQFDDA-------VSITIAILIVVTVAFI---QEYRSEKSLEELKKLVPPECHCLREGR- 231
            :|.::..|::.       |...:.:||:|..|.:   ||..:|.::|.||:..|......|:.|
 Frog    71 ISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRK 135

  Fly   232 -LDTFLARELVPGDIVHLNVGDRVPADVRL--FEAVDLSIDESSFTGETEPARKITDVLLNNTNV 293
             :....||::||||||.:.|||:||||:||  .::..|.:|:|..|||:....|.||.:.:...|
 Frog   136 SVQRIKARDIVPGDIVEVAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAV 200

  Fly   294 KDHSNMKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLS-F 357
              :.:.||:.|.||.:..|...|:||:||..:|.|::...|.|.|..:||||:.:|..|.||| .
 Frog   201 --NQDKKNMLFSGTNIAAGKAIGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKV 263

  Fly   358 YSFLIIGV-IMLLG----------WLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRM 411
            .|.:.|.| |:.:|          |::|  ....|.|:|:|||||||||||.|:|..||||..||
 Frog   264 ISLICIAVWIINIGHFNDPVHGGSWIRG--AIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRM 326

  Fly   412 AKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMAD--------VTGAGYND 468
            ||:|:||:.||:||||||.:|||||||||||.|:|:...:...|....|        :||:.|..
 Frog   327 AKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIVDKVEGDNCFLNEFNITGSTYAP 391

  Fly   469 QGEI----HIRHCNNVEMAKTNITNLLEIGAVCNNAYIQ----NGTL--LGQPTEGALVAVAMKN 523
            .||:    .:..|:..:    .:..|..|.|:||::.:.    .|..  :|:.||.||..:..|.
 Frog   392 MGEVLKDDKLVKCHQYD----GLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTCLVEKM 452

  Fly   524 GMYAT-AENYVRIQE-----------------YPFSSEQKMMAVKCI-HKYNNNKEEIFFAKGAL 569
            .::.| .:...||:.                 ..||.::|.|:|.|. :|.:.......|.|||.
 Frog   453 NVFDTDLKGLSRIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAP 517

  Fly   570 ETLLPQCTKYQFGTQTVPLT---KQNEAEFLAEAYEIGRKGLRVLALA--------KGRSMQD-- 621
            |.|:.:||..:.|:..||||   ||.....:.| :..||..||.||||        :..:::|
 Frog   518 EGLIDRCTHIRVGSIKVPLTAGIKQKIMSVIRE-WGTGRDTLRCLALATHDNPPRKEDMNLEDST 581

  Fly   622 --------LIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTH 678
                    |.:.|.||:.||||..|..|::|..|:|:||.|:|||.:.||:||  .||
 Frog   582 NFINYETNLTFVGCVGMLDPPRTEVAASVKMCRQAGIRVIMITGDNKGTAVAI--CRR------- 637

  Fly   679 AIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANLIGI----DTIHHQTLS 739
                                                             :||    :.:..:..:
 Frog   638 -------------------------------------------------VGIFREDEDVSERAFT 653

  Fly   740 GQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIA 804
            |:|.|:::.........|...|.||.|.||.:||:.||....|..||||||||..|||||:||||
 Frog   654 GREFDELSPAAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIA 718

  Fly   805 MGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDI 869
            || :||.|.|.|::|:|.:|:|.||:||:|||:.|:.|::.|:|:.:|:::..:..|.|...:..
 Frog   719 MG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGF 782

  Fly   870 ANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMIT-----KSVVVNVLLSASI 929
            ...|..:|:||:|::.||.||.:||..|.|.|::.:.|||.|:|:|:     :.:.:...:.|:.
 Frog   783 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAAT 847

  Fly   930 IVLGTLWVFQREMADG--------------------------TLGKTKRDTTMTFTCFVFFDMFN 968
            :.....|....|  ||                          .:.::....||..:..|..:|.|
 Frog   848 VGAAAWWFIAAE--DGPRITFYQLSHFLQCREENPDFDGVECEIFESPYPMTMALSVLVTIEMCN 910

  Fly   969 ALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTPYDIFFLVSLTSS 1033
            ||:..|:.:|:..:....|...|.::..|:....|::|..||.::||...|.......::.::..
 Frog   911 ALNSLSENQSLLRMPPWENVWLLGSICLSMSLHFLILYVEPLPLIFQITPLNLIQWLMVLKISLP 975

  Fly  1034 VLVVSEIKKWFERTMER 1050
            |:::.|..|:..|...|
 Frog   976 VILLDETLKYVARNYLR 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	331/1054 (31%)
		Cation_ATPase_N	112..179	CDD:279080	21/65 (32%)
		E1-E2_ATPase	191..425	CDD:278548	101/252 (40%)
		Cation_ATPase	496..579	CDD:289987	27/107 (25%)
		COG4087	<760..823	CDD:226572	37/62 (60%)
		Cation_ATPase_C	872..1044	CDD:279079	47/202 (23%)
atp2a2	XP_031748548.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100699at2759
OrthoFinder	1	1.000	-	-		FOG0000231
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010