Protein Alignment SPoCk and atp4a

DIOPT Version :10

• Sequence 1: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: XP_031762229.1
• Gene: atp4a / 100488221
• XenbaseID: XB-GENE-486104
• Length: 1031
• Species: Xenopus tropicalis
• Alignment Length: 1042
• Identity: 287/1042 - (27%)
• Similarity: 472/1042 - (45%)
• Gaps: 180/1042 - (17%)

  Fly   118 EVAGRLQVDVRTGLKWTEAKYRAKII---GHNELLLVAEDPTWKKYIEQFRNPLILLLLGSALVS 179
            |:..:...:|..|:|   |.:.|:|:   |.|||......|.:.|:..|....|..|:..:|::.
 Frog    57 ELEQKYNTNVTKGMK---ATFAAEILIRDGPNELKPPKGTPEYVKFARQLAGGLQCLMWVAAVIC 118

  Fly   180 VIMKQFDDA-----------VSITIAILIVVTVAF--IQEYRSEKSLEELKKLVPPECHCLREGR 231
            :|....:.|           ::||:..::|||..|  .||::|...:...|.|||.:...||:|.
 Frog   119 LIAFGIECAQGDLTSADNLYLAITLIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVLRDGE 183

  Fly   232 LDTFLARELVPGDIVHLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTNVKDH 296
            .....|.:||.||:|.:..|||||||:|:..:....:|.||.|||:||..:..:.        .|
 Frog   184 KFQINANQLVVGDLVEIKGGDRVPADIRIITSQGCKVDNSSLTGESEPQTRSPEY--------TH 240

  Fly   297 SN---MKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTP----LQKSMDILGAQ 354
            .:   .:||||..|:...|...|::::||:|:..|.:..:.......|||    ::..:||:...
 Frog   241 ESPLETRNIAFFSTMCLEGTATGVIINTGDRTIIGRIASLASGVGNEKTPIAIEIEHFVDIIAGL 305

  Fly   355 LSFYSFLIIGVIMLLGWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVK 419
            ..|:......|.|::|:    |........:::.||.:||||...|||.|:|...|:|::|.:||
 Frog   306 AIFFGATFFVVAMVIGY----PFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLARKNCVVK 366

  Fly   420 KLPTVETLGCVNVICSDKTGTLTKNEMTAT-IIITSDGYMADVTGAGYNDQGEIHIRHCNNVEMA 483
            .|..|||||..:|||||||||||:|.||.: :...:..:.||.|    .||........::...|
 Frog   367 NLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNQIHSADTT----EDQSGQSFDQTSDTWRA 427

  Fly   484 KTNITNLLEIGAVCNNAYIQNG---------TLLGQPTEGALV---AVAMKNGMYATAENYVRIQ 536
            .:.:|:|      ||.|..::|         .::|..:|.||:   .:.:.|.| ...:.:.:..
 Frog   428 LSKVTSL------CNRACFKSGQDGVPIPKRIVIGDASETALLKFSELTVGNVM-EYRDRFKKAT 485

  Fly   537 EYPFSSEQKMMAVKCIHKYNN--NKEEIFFAKGALETLLPQCTKYQFGTQTVPLTKQNEAEFLAE 599
            |.||:|..|...  .||:..:  :...:...|||.|.:|.:|:......|.:||.:|.:..|...
 Frog   486 ELPFNSTNKFQL--SIHELQDPLDLRYLLVMKGAPERILERCSTIMIKGQELPLDEQWKEAFQTA 548

  Fly   600 AYEIGRKGLRVLALA----------KGRSM---------QDLIYCGLVGITDPPRPLVRESIEML 645
            ..::|..|.|||...          :|.|.         ..|.:.||:.:.||||..|.:::...
 Frog   549 YMDLGGLGERVLGFCHLYLNEKEYPRGFSFDTEEMNFPTSGLCFAGLISMIDPPRATVPDAVMKC 613

  Fly   646 MQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEI 710
            ..:|:||.|||||...||.||..|..:.:..:..:........:|:...:...:..|:.|
 Frog   614 RTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRIPVEQVNKRDARACVIN----- 673

  Fly   711 YLTALAQQGLPLVTANLIGIDTIHHQTLSGQEMDQMNEHQLDKV-ANNVSVFYRVSPRHKLEIVK 774
                                        .||..|..:|..::.: .:...||.|.||:.||.||:
 Frog   674 ----------------------------GGQLKDMTSEELVEALKLHPEMVFARTSPQQKLIIVE 710

  Fly   775 SLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGI 839
            |.|:.|.||.:|||||||..||||||||:|||..|:|..|.||||||::|:|.:|:..:|:|:.|
 Frog   711 SCQKLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLI 775

  Fly   840 FYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLK 904
            |.|::..:.:.|:.:|..||...:.....:..||..:.||:|.:..|..|:.||..|..:.|::.
 Frog   776 FDNLKKSIAYTLTKNIPELAPYLIYITASVPLPLGCITILFIELCTDIFPSVSLAYERAESDIMH 840

  Fly   905 QKPRNVKQP-MITKSVVVNVLLSASII----------------------VLG--TLWVFQ--REM 942
            .||||.::. ::.:::.|.......||                      |||  :.|..|  :::
 Frog   841 LKPRNPRRDRLVNEALAVYSYFQVGIIQSFAGFVDYFTVMAQEGWFPAYVLGLRSHWENQHLQDL 905

  Fly   943 AD--GTLGKTKRDTTMTFTCF-VFF------DMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSI 998
            .|  |......:.....:.|: |||      .:.:.|..:::..|||..|...|::.::|:.|.:
 Frog   906 EDSYGQQWTFSQRLYQQYNCYTVFFISIEVCQIADVLIRKTRRLSVFQQGFFRNKVLVIAIVFQL 970

  Fly   999 IGQMLVVYFPPLQMVFQTEAL--------TPYDIFFLVSLTSSVLVVSEIKK---------WFER 1046
            .....:.|.|.:..||....:        .|:.|.        :.|..||:|         |:::
 Frog   971 CLGNFLCYCPGMPNVFNFMPIRFQWWLVPVPFGIL--------IFVYDEIRKLGVRRNPGSWYDK 1027

  Fly  1047 TM 1048
            .:
 Frog  1028 EL 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPoCk	NP_001262220.1	P-type_ATPase_SPCA	139..1042	CDD:319779	280/1004 (28%)
atp4a	XP_031762229.1	ATPase-IIC_X-K	39..1031	CDD:273445	287/1042 (28%)