Protein Alignment CG11241 and PHYKPL

DIOPT Version :10

• Sequence 1: NP_730741.2
• Gene: CG11241 / 40492
• FlyBaseID: FBgn0037186
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: XP_011532971.1
• Gene: PHYKPL / 85007
• HGNCID: 28249
• Length: 460
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 180/489 - (36%)
• Similarity: 258/489 - (52%)
• Gaps: 65/489 - (13%)

  Fly    47 NHRPAAYEGSTYEQILKTRRNHLTPNLLAHF-KKPLVIHAGHMQWLYDHEGRRYLDMFGGIVTVS 110
            :.||.|       ..|..|:..::.:....| :.|:.|.....|::||.:|..|:|....:  ..
Human     4 DQRPKA-------DTLALRQRLISSSCRLFFPEDPVKIVRAQGQYMYDEQGAEYIDCISNV--AH 59

  Fly   111 VGHCHPKVNQALSEQTAKLWHTTNIYMHPKIHEYAERLVAKFPGDLKSVCFVNSGSEANDLAMLM 175
            ||||||.|.||..||...| :|.:.|:|..|.:||:||....|..|....|:||||||||||:.:
Human    60 VGHCHPLVVQAAHEQNQVL-NTNSRYLHDNIVDYAQRLSETLPEQLCVFYFLNSGSEANDLALRL 123

  Fly   176 ARLYTGNQDILSLRNCYHG-------MSPYTM-GLTAHSTWRFPLPGVNSGLVHVMN-PDPYQGI 231
            ||.|||:||::.|.:.|||       :|||.. .|.....|           |||.. ||.|:|.
Human   124 ARHYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLDGQKEW-----------VHVAPLPDTYRGP 177

  Fly   232 WGGSNCRDSPVQTTRKCQCTVGCQAGDAYYNELEETFKYSLPRG-KVAAMFAESIQGVGGTVQFP 295
            :.    .|.|             ....||.||::.....:..:| |:||.||||:..|||.:..|
Human   178 YR----EDHP-------------NPAMAYANEVKRVVSSAQEKGRKIAAFFAESLPSVGGQIIPP 225

  Fly   296 KGYLKRAA----------ALVRANGGLFVADEVQTGFGRTGEHFWGF--ESHDYVPDIVTMAKGI 348
            .||..:.|          ..:|..||:|||||:|.||||.|:|||.|  :..|:|||||||.|.|
Human   226 AGYFSQVADPRVSHLLCHRHIRKAGGVFVADEIQVGFGRVGKHFWAFQLQGKDFVPDIVTMGKSI 290

  Fly   349 GNGFPLAAVVTTPEIAASL--SQALHFNTYGGNPMASAVGIAVLDVIEEEQLQRNSLEVGTYFLK 411
            |||.|:|.|..|..:|.:.  :...:|||:||:|::.|||:|||:|:|:||||.::..||::.::
Human   291 GNGHPVACVAATQPVARAFEATGVEYFNTFGGSPVSCAVGLAVLNVLEKEQLQDHATSVGSFLMQ 355

  Fly   412 GLAELQQRFEIIGDVRGKGLMIGVELVGNREKRTPLATPHVLDIWEKCKDQGVLLGRGGLHGNVL 476
            .|.:.:.:..|:|||||.||.|||:|:.:...||| ||.....:..:.|:..|||...|...|:|
Human   356 LLGQQKIKHPIVGDVRGVGLFIGVDLIKDEATRTP-ATEEAAYLVSRLKENYVLLSTDGPGRNIL 419

  Fly   477 SMRPPLCLCAEDVEFALETLEEAFKFHMSKSPRS 510
            ..:||:|...::....:..| :|....|.:..||
Human   420 KFKPPMCFSLDNARQVVAKL-DAILTDMEEKVRS 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11241	NP_730741.2	ArgD	59..501	CDD:439930	174/466 (37%)
PHYKPL	XP_011532971.1	PRK06148	<1..443	CDD:180426	177/478 (37%)