DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11241 and etnppl

DIOPT Version :9

Sequence 1:	NP_001303389.1	Gene:	CG11241 / 40492	FlyBaseID:	FBgn0037186	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_956743.1	Gene:	etnppl / 393421	ZFINID:	ZDB-GENE-040426-1133	Length:	492	Species:	Danio rerio

Alignment Length:	450	Identity:	191/450 - (42%)
Similarity:	277/450 - (61%)	Gaps:	35/450 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 EQILKTRRNHLTPNLLAHF-KKPLVIHAGHMQWLYDHEGRRYLDMFGGIVTVSVGHCHPKVNQAL 122
            ::.:..|:.|:.|:....| ..|:.|.....|::|:.:..:|||....:  ..||||||.|..|.
Zfish     9 QKTIDLRKKHVGPSCKVFFDHDPIKIVRAKGQYMYNEKDEKYLDCINNV--AHVGHCHPDVVSAG 71

  Fly   123 SEQTAKLWHTTNIYMHPKIHEYAERLVAKFPGDLKSVC-FVNSGSEANDLAMLMARLYTGNQDIL 186
            ::| .:|.:|.:.::|..:..||:||.|..|..| ||| ||||||||||||:.:|..|||::||:
Zfish    72 AKQ-MELLNTNSRFLHDSLVLYAQRLQATLPEKL-SVCYFVNSGSEANDLALRLAWQYTGHKDII 134

  Fly   187 SLRNCYHGMSPYTMGLTAHSTWRF-PLPGVN-SGLVHV-MNPDPYQGIWGGSNCRDSPVQTTRKC 248
            :|.|.|||   :...|...|.::| .:.|.. |..||| ::||.|:|.:.    .|.|...|
Zfish   135 TLDNAYHG---HVSSLIDISPYKFHQMAGAEPSQHVHVALSPDTYRGKYR----EDHPDPAT--- 189

  Fly   249 QCTVGCQAGDAYYNELEETFKYSLPRG-KVAAMFAESIQGVGGTVQFPKGYLKRAAALVRANGGL 312
                      ||...::|..:.:..:| ::||..|||:|..||.|..|.||.::.|..||..||:
Zfish   190 ----------AYAENVKEVIEEAHKKGHEIAAFIAESLQSCGGQVIPPMGYFQKVAQHVRNAGGI 244

  Fly   313 FVADEVQTGFGRTGEHFWGF--ESHDYVPDIVTMAKGIGNGFPLAAVVTTPEIAAS-LSQAL-HF 373
            |:|||||.||||.|.|||||  :..|:|||||||.|.||||.|::.|:|:.|||.| :|..: :|
Zfish   245 FIADEVQVGFGRVGTHFWGFQLQGEDFVPDIVTMGKPIGNGHPMSCVITSREIAESFMSSGMEYF 309

  Fly   374 NTYGGNPMASAVGIAVLDVIEEEQLQRNSLEVGTYFLKGLAELQQRFEIIGDVRGKGLMIGVELV 438
            ||:||||::.|:|:|||:|||:|.||.|:|.||.|..:.|.:|::|..::|||||:||.:|:|||
Zfish   310 NTFGGNPVSCAIGLAVLNVIEKEDLQGNALHVGGYLTQLLEDLKKRHPLVGDVRGRGLFVGLELV 374

  Fly   439 GNREKRTPLATPHVLDIWEKCKDQGVLLGRGGLHGNVLSMRPPLCLCAEDVEFALETLEE 498
            .|:.|||| ||....::..:.|:|.:||...|.|.|||..:||:|...||.|||:|.:::
Zfish   375 RNQSKRTP-ATAEAQEVIYRLKEQRILLSADGPHRNVLKFKPPMCFSREDAEFAVEKIDQ 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11241	NP_001303389.1	GabT	55..501	CDD:223238	191/449 (43%)
CG11241	NP_001303389.1	OAT_like	80..500	CDD:99735	187/427 (44%)
etnppl	NP_956743.1	GabT	12..439	CDD:223238	191/446 (43%)
		OAT_like	25..435	CDD:99735	188/433 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	462..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63788
OrthoDB	1	1.010	-	-		D145181at2759
OrthoFinder	1	1.000	-	-		FOG0000701
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830