DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11367 and XPNPEP2

DIOPT Version :9

Sequence 1:	NP_649412.1	Gene:	CG11367 / 40491	FlyBaseID:	FBgn0037185	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_003390.4	Gene:	XPNPEP2 / 7512	HGNCID:	12823	Length:	674	Species:	Homo sapiens

Alignment Length:	201	Identity:	42/201 - (20%)
Similarity:	64/201 - (31%)	Gaps:	52/201 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 MQKPVPASTAPAFPQLIQASCSNAVEVD-----------PPDSIVGAAGNSEALFAAQRTPDTSE 80
            ::|.||..|...|        |.|..||           |....:.|:|.:.||.....|.:.:.
Human   383 LEKNVPKGTVDEF--------SGAEIVDKFRGEEQFSSGPSFETISASGLNAALAHYSPTKELNR 439

  Fly    81 DSECDP-FLASRRATRSSATTSVLHNRKRNSCWGRAHSFLTRNWYLGCLVPATILGALVF----I 140
            ....|. :|..........||.:    .|...||...:| .:..|...|:....|..|:|    .
Human   440 KLSSDEMYLLDSGGQYWDGTTDI----TRTVHWGTPSAF-QKEAYTRVLIGNIDLSRLIFPAATS 499

  Fly   141 GWATRDYARQLLFWIEMQNAWITFAVYMGLFALVSFPVVVGYFVLLITAGYLFGCLRGWVTVILG 205
            |.....:||:.| |    :|.:.:....|        ..:|.|:          |:..|......
Human   500 GRMVEAFARRAL-W----DAGLNYGHGTG--------HGIGNFL----------CVHEWPVGFQS 541

  Fly   206 ANIGIA 211
            .||.:|
Human   542 NNIAMA 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11367	NP_649412.1	DedA	150..340	CDD:223659	11/62 (18%)
CG11367	NP_649412.1	SNARE_assoc	180..298	CDD:286425	7/32 (22%)
XPNPEP2	NP_003390.4	Creatinase_N	54..184	CDD:279639
		Creatinase_N_2	202..361	CDD:292807
		PepP	<348..601	CDD:223085	42/201 (21%)
		APP	365..583	CDD:238518	42/201 (21%)
		Peptidase_M24_C	585..648	CDD:292806
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900