DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11367 and tmem41b

DIOPT Version :9

Sequence 1:	NP_649412.1	Gene:	CG11367 / 40491	FlyBaseID:	FBgn0037185	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001016955.1	Gene:	tmem41b / 549709	XenbaseID:	XB-GENE-978007	Length:	278	Species:	Xenopus tropicalis

Alignment Length:	210	Identity:	40/210 - (19%)
Similarity:	84/210 - (40%)	Gaps:	45/210 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 FWIEMQNAWITFAVYMGLFALVSFPVVVGYFVLLITAGYLFGCLRGWVTVILGANIGIAVAHATI 217
            |::|:..|:.|..:::..||      :.|...|.|.:|:|:........|.|.:.:|.:..:
Frog    96 FYVEVLVAYFTTYIFLQTFA------IPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCY--- 151

  Fly   218 RSCRHRIPVQRLIKNDTGRAILRVISGPKAFR--------------VVLFTRLTP-IPFGVQNVI 267
                       |:....||.::......||.:              .::|.|:|| :|....|:.
Frog   152 -----------LLSYLVGRPVVYKYLSDKAIKWSQQVERHRDHLINYIIFLRITPFLPNWFINIT 205

  Fly   268 FGISSINTRDYHVATLIGLLPAQTINVYLGSTLRSM---HEVLSDNDTKLTGYISFLFEVICGVA 329
            ..:.::..:.:.:.|.||:.|...:.:..|:||..:   .|.:|.|..       .:..|:..::
Frog   206 SPVINVPLKVFFLGTFIGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSV-------IILMVLAVLS 263

  Fly   330 LMFWVLQKARKELSE 344
            ::..:.||..|:..|
Frog   264 ILPAIFQKKLKKKFE 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11367	NP_649412.1	DedA	150..340	CDD:223659	38/204 (19%)
CG11367	NP_649412.1	SNARE_assoc	180..298	CDD:286425	23/132 (17%)
tmem41b	NP_001016955.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		VTT	116..235	CDD:378149	23/132 (17%)
		VTT domain, required for its function in autophagy. /evidence=ECO:0000250\|UniProtKB:Q5BJD5	127..238		21/124 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910