DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11367 and Tmem41b

DIOPT Version :9

Sequence 1:NP_649412.1 Gene:CG11367 / 40491 FlyBaseID:FBgn0037185 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_001012358.1 Gene:Tmem41b / 361626 RGDID:1310870 Length:291 Species:Rattus norvegicus


Alignment Length:313 Identity:57/313 - (18%)
Similarity:116/313 - (37%) Gaps:68/313 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 DSIVGAAGNSEALFAAQRTPDTSEDSECDPFLASRRATRSSATTSVLHNRKRNSCWGRAHSFLTR 121
            |..||..|:     ||....|..::..|        ....||.||:|......||.......:.:
  Rat    22 DRAVGTQGS-----AAPGNKDHLKEKPC--------VEAGSARTSLLILVSIFSCAAFVMFLVYK 73

  Fly   122 NW-------YLGCLVPATILGALVFIGWATRDYARQLLFWIEMQNAWITFAVYMGLFALVSFPVV 179
            |:       .:...||..:..|.. :|.....|  :..|::::..|:....:::..||      :
  Rat    74 NFPQLSEEERVNMKVPRDMDDAKA-LGKVLSKY--KDTFYVQVLVAYFATYIFLQTFA------I 129

  Fly   180 VGYFVLLITAGYLFGCLRGWVTVILGANIGIAVAHATIRSCRHRIPVQRLIKNDTGRAILRVISG 244
            .|...|.|.:|:|:........|.|.:.:|.:..:              ::....||.::.....
  Rat   130 PGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCY--------------MLSYLVGRPVVYKYLT 180

  Fly   245 PKAFR--------------VVLFTRLTP-IPFGVQNVIFGISSINTRDYHVATLIGLLPAQTINV 294
            .||.:              .::|.|:|| :|....|:...:.::..:.:.:.|.:|:.|...:.:
  Rat   181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAI 245

  Fly   295 YLGSTLRSM---HEVLSDNDTKLTGYISFLFEVICGVALMFWVLQKARKELSE 344
            ..|:||..:   .|.:|.|..       |:..::..::::..:.||..|:..|
  Rat   246 KAGTTLYQLTTAGEAVSWNSV-------FILMILALLSILPAIFQKKLKQKFE 291

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11367NP_649412.1 DedA 150..340 CDD:223659 34/207 (16%)
SNARE_assoc 180..298 CDD:286425 21/132 (16%)
Tmem41bNP_001012358.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..38 6/20 (30%)
SNARE_assoc 129..248 CDD:401323 21/132 (16%)
VTT domain, required for its function in autophagy. /evidence=ECO:0000250|UniProtKB:Q5BJD5 140..251 19/124 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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