DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11367 and AgaP_AGAP012406

DIOPT Version :9

Sequence 1:	NP_649412.1	Gene:	CG11367 / 40491	FlyBaseID:	FBgn0037185	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	XP_551778.3	Gene:	AgaP_AGAP012406 / 3291575	VectorBaseID:	AGAP012406	Length:	277	Species:	Anopheles gambiae

Alignment Length:	269	Identity:	147/269 - (54%)
Similarity:	195/269 - (72%)	Gaps:	16/269 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 HNRKRNSCWG----RAHSFL---------TRNWYLGCLVPATILGALVFIGWATRDYARQLLFWI 155
            ::|||:|..|    ...|:|         .|......|:|..:|..::.:.:..||.|:.:||||
Mosquito     2 NDRKRSSIDGDTIAMRDSWLYRLQRIVASQRRPMFSYLLPLCLLIGIMLLIYTFRDTAKGVLFWI 66

  Fly   156 EMQNAWITFAVYMGLFALVSFPVVVGYFVLLITAGYLFGCLRGWVTVILGANIGIAVAHATIRSC 220
            |.||.||.|.:::.:|.:|||||.|||.||:|.:|||||.:||.:||::|||:|:|:||.||:|.
Mosquito    67 ETQNTWIIFVIFLCMFTVVSFPVTVGYLVLIIASGYLFGFIRGLLTVVIGANLGVAIAHNTIKSL 131

  Fly   221 RHRIPVQRLIKNDTGRAILRVISGPKAFRVVLFTRLTPIPFGVQNVIFGISSINTRDYHVATLIG 285
            :.::||.:||:|:||||||||||||:||::|||.||||||||:||.||||||:|||.||..|:||
Mosquito   132 QSKLPVHKLIRNETGRAILRVISGPRAFKIVLFARLTPIPFGLQNTIFGISSVNTRSYHAGTVIG 196

  Fly   286 LLPAQTINVYLGSTLRSMHEVLSDNDTK--LTGYISFLFEVICGVALMFWVLQKARKELSETLL- 347
            |||||||||||||.|||:||||||::..  |.||..|:.|||.|.|||.||:||||.|||..||
Mosquito   197 LLPAQTINVYLGSKLRSIHEVLSDHNAALGLAGYGVFVVEVIVGAALMIWVIQKARLELSAALLA 261

  Fly   348 SADYNNEGK 356
            :.|.:::.|
Mosquito   262 TTDADSDEK 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11367	NP_649412.1	DedA	150..340	CDD:223659	125/191 (65%)
CG11367	NP_649412.1	SNARE_assoc	180..298	CDD:286425	82/117 (70%)
AgaP_AGAP012406	XP_551778.3	SNARE_assoc	91..209	CDD:286425	82/117 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	177	1.000	Domainoid score	I7430
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45636
Inparanoid	1	1.050	284	1.000	Inparanoid score	I5248
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003179
OrthoInspector	1	1.000	-	-		otm50385
Panther	1	1.100	-	-	LDO	PTHR46593
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5452
TreeFam	1	0.960	-	-
	10	10.020