Protein Alignment CG11367 and TMEM64

DIOPT Version :9

• Sequence 1: NP_649412.1
• Gene: CG11367 / 40491
• FlyBaseID: FBgn0037185
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001008495.2
• Gene: TMEM64 / 169200
• HGNCID: 25441
• Length: 380
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 102/348 - (29%)
• Similarity: 170/348 - (48%)
• Gaps: 49/348 - (14%)

  Fly    38 AFPQLIQ-ASCSNAVEV-------------DPPDSIVGAAGNSEALFAAQRT------------- 75
            |.|:|:| |:.....|:             .|.|.:....|.|.|..||..:
Human    11 ALPRLLQHAALPGLAELPARWALPRGAGGDGPADRLPRGGGASAAAAAAAASGALLGAYLERHGP 75

  Fly    76 PDTSEDSECDPFLASRRATRSSAT---TSVLHNRK----RNSCWGRAHSFLTRNWYLGCLVPATI 133
            |:.||..|....||....:.....   .:.:.|.:    .::||.|:            ||...:
Human    76 PEASELPEPGGALAGGPGSGGGGVVVGVAEVRNWRCCCLGSTCWCRS------------LVLVCV 128

  Fly   134 LGALVFIGWA-TRDYARQLLFWIEMQNAWITFAVYMGLFALVSFPVVVGYFVLLITAGYLFGCLR 197
            |.||.|...| .|.|...||.|:|..::.:...:::..|.:||||...||.||.:.||||:|.:.
Human   129 LAALCFASLALVRRYLHHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGFVL 193

  Fly   198 GWVTVILGANIGIAVAHATIRSCRHRIPVQRLIKNDTGRAILRVISGPKAFRVVLFTRLTPIPFG 262
            |...:::|..||..:||...:.........|:..::...|::||:.|....:||...||||||||
Human   194 GMGLMMVGVLIGTFIAHVVCKRLLTAWVAARIQSSEKLSAVIRVVEGGSGLKVVALARLTPIPFG 258

  Fly   263 VQNVIFGISSINTRDYHVATLIGLLPAQTINVYLGSTLRSMHEVLSDNDTKLTGYISFLFEVICG 327
            :||.:|.|:.::..:|.:|:.:||||.|.:|.|||:|||:|.:|:::.  .::||..|..::|..
Human   259 LQNAVFSITDLSLPNYLMASSVGLLPTQLLNSYLGTTLRTMEDVIAEQ--SVSGYFVFCLQIIIS 321

  Fly   328 VALMFWVLQKARKELSETLLSAD 350
            :.|||:|:.:|:.||:..:::.:
Human   322 IGLMFYVVHRAQVELNAAIVACE 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11367	NP_649412.1	DedA	150..340	CDD:223659	68/189 (36%)
		SNARE_assoc	180..298	CDD:286425	44/117 (38%)
TMEM64	NP_001008495.2	TVP38	123..294	CDD:223475	62/170 (36%)
		VTT domain. /evidence=ECO:0000250|UniProtKB:P36164	186..296		40/109 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141891
Domainoid	1	1.000	89	1.000	Domainoid score	I7880
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45636
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4338
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1327131at2759
OrthoFinder	1	1.000	-	-		FOG0003179
OrthoInspector	1	1.000	-	-		oto89865
orthoMCL	1	0.900	-	-		OOG6_101862
Panther	1	1.100	-	-	LDO	PTHR46593
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5552
SonicParanoid	1	1.000	-	-		X5452
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.890