DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11367 and AgaP_AGAP000476

DIOPT Version :9

Sequence 1:	NP_649412.1	Gene:	CG11367 / 40491	FlyBaseID:	FBgn0037185	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	XP_310616.4	Gene:	AgaP_AGAP000476 / 1271763	VectorBaseID:	AGAP000476	Length:	653	Species:	Anopheles gambiae

Alignment Length:	322	Identity:	64/322 - (19%)
Similarity:	106/322 - (32%)	Gaps:	73/322 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 VGAAGNSEALFAAQRTPDTSEDSECDPFLASRRATRSSATTSV-------LHNRKRNSCWGRAHS 117
            :|.|.|.:...|..|||     ...|..||..|:.....:...       .||.:..|...|...
Mosquito    25 LGRALNKDDELAEDRTP-----KSMDVILAEIRSLMRDYSIEAYIVPSVDAHNSEYISEHDRRLQ 84

  Fly   118 FLTRNWYLGCLVPATI-LGALVFIGWATRDY---------------ARQLLFWIEMQNAWITFAV 166
            ::|.  :.|....|.| ||....  |....|               .|:.|..:..::.|
Mosquito    85 YVTN--FTGSAGTAIIMLGKAAL--WTDSRYHLQADGELDAAHWTLMREGLPGVPTRDEW----- 140

  Fly   167 YMGLFALVSFPVVVGYFVLLITA---GYLFGCL--RGWVTVILGAN-----------------IG 209
               |.|.:|...:||....||.:   |.|...|  ||:..:.|..|                 :.
Mosquito   141 ---LLANLSPGALVGTDPFLIASTEYGRLGAVLAQRGYRLIALERNLVDIVWNNRPPQTADELLP 202

  Fly   210 IAVAHATIRSCRHRIPVQRLIKNDTGRAILRVISGPKAFRVVLFTRLTPIPFGVQNVIFGISSIN 274
            :.:|::..|:......|:..::.....||  ::|.......:|..|.:.|.:  ..|.|....::
Mosquito   203 LPLAYSGRRAADKVQAVRVTLQEHGANAI--IVSALDEIAWLLNLRGSDILY--NPVFFAYLIVS 263

  Fly   275 TRDYHVATLIGLLPAQTINVYL------GSTLRSMHEVLSDNDTKLTGYISFLFEVICGVAL 330
            ....|:.|....:.| |:..:|      |..:|...::|...|..:.|....:....|..||
Mosquito   264 HTHLHLYTNADRINA-TVRAHLASEGVGGLEVRDYRDILPGIDEYVRGGNRLMVSTACSQAL 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11367	NP_649412.1	DedA	150..340	CDD:223659	40/209 (19%)
CG11367	NP_649412.1	SNARE_assoc	180..298	CDD:286425	27/145 (19%)
AgaP_AGAP000476	XP_310616.4	Creatinase_N_2	198..351	CDD:292807	24/132 (18%)
		PepP	203..567	CDD:223085	24/127 (19%)
		APP	354..573	CDD:238518
		Peptidase_M24_C	587..648	CDD:292806
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900