DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11367 and AgaP_AGAP001037

DIOPT Version :9

Sequence 1:	NP_649412.1	Gene:	CG11367 / 40491	FlyBaseID:	FBgn0037185	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	XP_560264.4	Gene:	AgaP_AGAP001037 / 1270529	VectorBaseID:	AGAP001037	Length:	619	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	64/291 - (21%)
Similarity:	89/291 - (30%)	Gaps:	97/291 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 SEDSECDPFLASRRATRS-------SATTSVLHNRKRNSCW--GRAHSFLTR----NWYL----- 125
            |.|:....:||:|...|:       ||.|:|:..|:. ..|  ||.:...|:    ||.|
Mosquito    32 SNDAHQSEYLAARDERRAFVSGFDGSAGTAVVTEREA-LLWTDGRYYQQATKQLDTNWTLMRDGQ 95

  Fly   126 -------GCLVPATILGALVFIGWATRDYARQLLFWIEMQNAWITFAVYMGLFALVSFPVVVGYF 183
                   ..|..|...||.|.:.......|           ||:.....:........|||....
Mosquito    96 PSTPSIDAWLAKALQPGARVGVDANLITAA-----------AWMPLQTSLKTAGCTLLPVVPNLI 149

  Fly   184 VLLITAGYLFGCLRGW--------------VTVILGANIGIAVAHATIRSCRHRIPVQRLIKNDT 234
            .||            |              .|...||.  ||...||:|.           |...
Mosquito   150 DLL------------WKEQPAVPHNPLLPLATTFTGAT--IAQKLATVRE-----------KLAD 189

  Fly   235 GRAILRVISGPKAFRVVLFTRLTPIPFGVQNVIFGISSINTRDYHVATLIGLLPAQ--------- 290
            .||.:.|:|.......:|..|.|.|.:   |.:|....|.|.|   |..:.:.|||
Mosquito   190 KRASVLVVSALDEIAWLLNLRGTDIDY---NPVFFAYVIVTPD---ALYLFIDPAQMRPQVEDHF 248

  Fly   291 -----TINVY-LGSTLRSMHEVLSDNDTKLT 315
                 |:.|. .|.....:.|:..::.|..|
Mosquito   249 RANGVTVEVRGYGEVHAVLQELAGNSSTSAT 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11367	NP_649412.1	DedA	150..340	CDD:223659	40/195 (21%)
CG11367	NP_649412.1	SNARE_assoc	180..298	CDD:286425	31/146 (21%)
AgaP_AGAP001037	XP_560264.4	Creatinase_N	8..152	CDD:304957	29/131 (22%)
		Creatinase_N_2	162..324	CDD:292807	32/137 (23%)
		PepP	171..546	CDD:223085	31/128 (24%)
		APP	327..552	CDD:238518
		Peptidase_M24_C	557..619	CDD:292806
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900