DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11367 and tmem64

DIOPT Version :9

Sequence 1:	NP_649412.1	Gene:	CG11367 / 40491	FlyBaseID:	FBgn0037185	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	XP_004915209.2	Gene:	tmem64 / 100492114	XenbaseID:	XB-GENE-6076037	Length:	315	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	86/251 - (34%)
Similarity:	139/251 - (55%)	Gaps:	21/251 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 CWGRAHSFLTRNWYLGCLVPATILGALVFIGWATRDYARQLLFWIEMQNAWITFAVYMGLFALVS 175
            ||.|:...|       |.:.|....:|..    .|.|.:.:|.|:|..::.:...:::..|.|||
Frog    57 CWCRSAVLL-------CALSAVCCASLAM----GRHYLKDVLLWLESLDSLVGMLLFIVGFILVS 110

  Fly   176 FPVVVGYFVLLITAGYLFGCLRGWVTVILGANIGIAVAHATIRSCRHRIPVQRLIKNDTGR---A 237
            .|.|.||.||.:.||||:|.:.|...|::|..||..:||..   |:..:....|.|..|..   |
Frog   111 LPCVWGYIVLNVAAGYLYGLVLGIGLVVVGVLIGTFIAHLL---CKKLLTHWVLAKIHTSHKLGA 172

  Fly   238 ILRVISGPKAFRVVLFTRLTPIPFGVQNVIFGISSINTRDYHVATLIGLLPAQTINVYLGSTLRS 302
            ::||:.|....:||...||||||||:||.:|.|:.::..:|..|:.|||.|.|.:|.|||:|||:
Frog   173 VIRVVEGGSGLKVVALARLTPIPFGLQNAVFSITDLSLPNYLAASSIGLFPTQLLNSYLGTTLRT 237

  Fly   303 MHEVLSDNDTKLTGYISFLFEVICGVALMFWVLQKARKELSETLLSA--DYNNEGK 356
            :.:|:::.  .::||..|..:||..:||||:|:.:|:.||:..:::.  ::...||
Frog   238 IEDVIAEQ--SVSGYFIFSLQVIISIALMFYVVHRAQVELNAAIIACEMEFKTSGK 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11367	NP_649412.1	DedA	150..340	CDD:223659	73/192 (38%)
CG11367	NP_649412.1	SNARE_assoc	180..298	CDD:286425	48/120 (40%)
tmem64	XP_004915209.2	TVP38	63..233	CDD:223475	63/183 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7989
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45636
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4295
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1327131at2759
OrthoFinder	1	1.000	-	-		FOG0003179
OrthoInspector	1	1.000	-	-		oto103677
Panther	1	1.100	-	-	LDO	PTHR46593
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5552
SonicParanoid	1	1.000	-	-		X5452
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100