Protein Alignment mael and Mael

DIOPT Version :9

• Sequence 1: NP_788566.1
• Gene: mael / 40489
• FlyBaseID: FBgn0016034
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_780505.1
• Gene: Mael / 98558
• MGIID: 2138453
• Length: 434
• Species: Mus musculus
• Alignment Length: 469
• Identity: 92/469 - (19%)
• Similarity: 174/469 - (37%)
• Gaps: 118/469 - (25%)

  Fly     7 SGFMMFVNEWRNRNAEGRRMTL-----AQAVSHCGTIW--------EPFQKMNTQQRGPYNSGGK 58
            :.:..||.|   :..|.||..|     |.|:.:|...|        |.:.:|..:.|.   :.||
Mouse     9 NAYYFFVQE---KIPELRRRGLPVARVADAIPYCSADWALLREDEKEKYSEMAREWRA---AQGK 67

  Fly    59 DANVAQRAKRESSNGHGQVDKAQR------EATESLMDMKRTIERLVLNAKMSHDLENAKFVFVA 117
            |:..:::.|..|:       ..:|      :.:.|..||..      |:.|....|....|.|:
Mouse    68 DSGPSEKQKLVST-------PLRRPGMLVPKPSISPPDMSN------LSIKSDQALLGGIFYFL- 118

  Fly   118 FNYFTKA----LTTDVYVPAEFAACEYSLKEGIRSIYSTMIDPGQIIFGQGSDALLHSSTTHDLP 178
             |.|:..    .....::|.|....:|||:|||.:.:.:.|.||:|..|........|.::|.:|
Mouse   119 -NIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFIHPGEIPRGFRFHCQAASDSSHKIP 182

  Fly   179 LPPNALGEKNMTKLYRNIVDYLSKCQGKGKTLVVFTPAENITMVKSCFRYLECDDDFRDGGEKIQ 243
            :.....|....|.| :|:..::.  ...|....::..:::...|..|.:.:|...:.|...|.:.
Mouse   183 ISNFEFGHDQATVL-QNLYKFIH--PNPGNWPPIYCKSDDRARVNWCLKRMERASEIRQDLELLT 244

  Fly   244 VFDIQYLLFILKKEVMNVADLNDEKINKFATDAFFKK----DFFEFTAGIACQYHEDNDRTKYCT 304
            |.|:             |..:..:|..|..:..:.:.    ..:::::...|::||:|| ..:|.
Mouse   245 VEDL-------------VVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEEND-ILFCA 295

  Fly   305 QSMVTRWAYTFTDFMCGDLAITVQPGKHIPAQ-------------------------TKPNYLII 344
            .::..:.||..::.:.....|.: .|.|:|.|                         ..|.:...
Mouse   296 LAVCKKIAYCISNSLATLFGIQL-TGAHVPLQDYEASNSVTPKMVVLDAGRYQKLRVESPGFCHF 359

  Fly   345 SSYASSLDHESSFDSFY------------SLPGSGVKK--ES---------QPEACSLSSSRLSV 386
            :||  :.:..|:..:.|            |:.|.|:.:  ||         :..:|..|.|..:.
Mouse   360 NSY--NQEQRSNTSTGYYPSGVKISGPHSSVRGRGITRLLESISNSSNNIHRFSSCETSLSPYTP 422

  Fly   387 ASSSYKPIDHTSFA 400
            ....|||.  :||:
Mouse   423 QKDGYKPF--SSFS 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mael	NP_788566.1	Maelstrom	126..339	CDD:289764	44/241 (18%)
Mael	NP_780505.1	HMG_box_2	5..72	CDD:286146	17/68 (25%)
		Maelstrom	130..326	CDD:289764	43/213 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837957
Domainoid	1	1.000	55	1.000	Domainoid score	I11119
eggNOG	1	0.900	-	-		E1_28M7A
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13143
Inparanoid	1	1.050	57	1.000	Inparanoid score	I5423
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47416
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009912
OrthoInspector	1	1.000	-	-		oto94140
orthoMCL	1	0.900	-	-		OOG6_109678
Panther	1	1.100	-	-	LDO	PTHR21358
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4636
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790