DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14451 and Zfp366

DIOPT Version :9

Sequence 1:	NP_649410.1	Gene:	CG14451 / 40488	FlyBaseID:	FBgn0037183	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	XP_038959405.1	Gene:	Zfp366 / 100360041	RGDID:	2322904	Length:	743	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	50/177 - (28%)
Similarity:	70/177 - (39%)	Gaps:	40/177 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CEWCGKVYKSLVRYHNHIVCTHKLPVPDHQLVNCFHCPRSDCRFHKHGPGVQNFRQIGRLRRHYQ 86
            |..|||::|.|...|.|:: ||:...| |:...|          ||      .|.|...|:||..
  Rat   280 CSRCGKLFKQLSHLHTHML-THQGTRP-HKCQVC----------HK------AFTQTSHLKRHMM 326

  Fly    87 EKHMTGHLTCEYCQKQFQLKSALVAHRCRLRHPAIR---------DSQSAITLGRHVCKKGYTHL 142
            :........|..|.:.|...|.|.||..  :|.:.|         |..:...|.||:.    ||.
  Rat   327 QHSEVKPHNCRVCSRGFAYPSELKAHEA--KHASGRENICVECGLDFPTLAQLKRHLT----THR 385

  Fly   143 GALQRRLTCCQHGTPNTPTEDQ------KDIRDTVCLQCNKEYVDTH 183
            |.:|...:.|.. |...|::.|      ||||..:|.:|..|:|..|
  Rat   386 GPIQYNCSECDK-TFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPH 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14451	NP_649410.1	None
Zfp366	XP_038959405.1	PRK10263	<51..>227	CDD:236669
		COG5048	250..>546	CDD:227381	50/177 (28%)
		C2H2 Zn finger	252..272	CDD:275368
		C2H2 Zn finger	280..300	CDD:275368	8/20 (40%)
		C2H2 Zn finger	308..328	CDD:275368	8/35 (23%)
		C2H2 Zn finger	336..356	CDD:275368	7/21 (33%)
		C2H2 Zn finger	364..384	CDD:275368	4/23 (17%)
		C2H2 Zn finger	392..412	CDD:275368	4/20 (20%)
		C2H2 Zn finger	420..440	CDD:275368	5/12 (42%)
		C2H2 Zn finger	448..468	CDD:275368
		C2H2 Zn finger	476..496	CDD:275368
		C2H2 Zn finger	504..524	CDD:275368
		C2H2 Zn finger	532..551	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910