| Sequence 1: | NP_001097664.2 | Gene: | ArfGAP3 / 40487 | FlyBaseID: | FBgn0037182 | Length: | 553 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055531.1 | Gene: | ACAP1 / 9744 | HGNCID: | 16467 | Length: | 740 | Species: | Homo sapiens |
| Alignment Length: | 360 | Identity: | 80/360 - (22%) |
|---|---|---|---|
| Similarity: | 127/360 - (35%) | Gaps: | 85/360 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 AAGPSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRST 69
Fly 70 NLDTNWTWLQLRQMQLGGNANAAQFFRAH-----------NCSTTDAQVKYNSRAAQLYRDKLCA 123
Fly 124 QAQQAMKTHGTKLHLEQTDKSEGNEAAR-----------------------------EEDFFAQC 159
Fly 160 DNEVDFNVQNNNVSKQDPNPPTVAPVIS----VETQQGGAPSVNLL------NSVVPAAVPSSIG 214
Fly 215 ARKVQPKKGGLG----ARKVG--GLGATKVKTNFADIEARANAANEMKTSA---AAAPVVKPQTA 270
Fly 271 EDELETVASMRLAYQELSMQKTREEAKLKTMDPAK 305 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ArfGAP3 | NP_001097664.2 | ArfGap | 17..121 | CDD:214518 | 32/114 (28%) |
| ACAP1 | NP_055531.1 | Required for formation of endosomal tubules when overexpressed with PIP5K1C | 1..382 | ||
| BAR | 18..217 | CDD:299863 | |||
| PH | 266..360 | CDD:278594 | |||
| PH_ACAP | 268..364 | CDD:270070 | |||
| Required for interaction with GULP1 | 405..740 | 78/351 (22%) | |||
| ArfGap | 406..519 | CDD:279720 | 34/132 (26%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 525..581 | 6/60 (10%) | |||
| Prevents interaction with ITGB1 when S-554 is not phosphorylated | 525..566 | 3/40 (8%) | |||
| ANK | <592..692 | CDD:238125 | 25/100 (25%) | ||
| ANK repeat | 606..637 | CDD:293786 | 6/30 (20%) | ||
| Ank_5 | 626..680 | CDD:290568 | 15/54 (28%) | ||
| ANK repeat | 639..670 | CDD:293786 | 10/31 (32%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||