Protein Alignment ArfGAP3 and GLO3

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_011048.1
• Gene: GLO3 / 856859
• SGDID: S000000924
• Length: 493
• Species: Saccharomyces cerevisiae
• Alignment Length: 571
• Identity: 144/571 - (25%)
• Similarity: 235/571 - (41%)
• Gaps: 137/571 - (23%)

  Fly     9 SKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDT 73
            ::|..:.||.:|.:...|:.||||..|.|||:||.:|:.:||.|||||||:|||:|||:|:.||
Yeast    11 TEQTTQQVFQKLGSNMENRVCFDCGNKNPTWTSVPFGVMLCIQCSAVHRNMGVHITFVKSSTLD- 74

  Fly    74 NWTWLQLRQMQLGGNANAAQFFRAH------NCSTTDAQVKYNSRAAQLYRDKLCAQAQQAMKTH 132
            .||...||:.:||||..|..||..:      |.:..||:.||.|..|:.|:..|..:.|:.|:.:
Yeast    75 KWTINNLRRFKLGGNHKARDFFLKNNGKQLLNTANVDAKTKYTSPVAKKYKIHLDKKVQKDMELY 139

  Fly   133 GTKLHLEQTDKSEG-----NEAARE-------EDFFAQCDNEVDFNVQNNNVSKQDPNPPTVAPV 185
            .::|.|...|.|:.     ::|:|.       :|||:.....     .:|:.||.:.|..::||
Yeast   140 PSELVLNGQDSSDSPLDTDSDASRSTSKENSVDDFFSNWQKP-----SSNSSSKLNVNTGSLAP- 198

  Fly   186 ISVETQQGGAPSVNLL---NSVVPAAVPSSIGARKVQPKKGGLGARKVGGLGATKVKTNFADIEA 247
              .....|..|...:.   :|::.|                   :||       |...|..|.:.
Yeast   199 --KNNTTGSTPKTTVTKTRSSILTA-------------------SRK-------KPVLNSQDKKK 235

  Fly   248 RANAANEMKTSAAAAPVVKPQTAEDELETVASMRLAYQELSMQKTREEAKLKTMDPAKAKQMERL 312
            .:..::..|.:...|..|....|||..:..  .:.|.||...:.|...:..|........|....
Yeast   236 HSILSSSRKPTRLTAKKVDKSQAEDLFDQF--KKEAQQEKEDEFTNSSSSTKIRQNDYDSQFMNN 298

  Fly   313 GMGFNLRGSDMAHSALGDMETIQQSAAPKAKLSLLESENFFTDFSLYGNSSSGGGGGGSSEKRES 377
            ..|.|       ::::.|:.|               ..:.|.||.   |.:|........|::::
Yeast   299 SKGNN-------NNSIDDINT---------------QPDEFNDFL---NDTSNSFDTTRKEQQDT 338

  Fly   378 SVGGTSKLDKFELDALGYETIEPIGGSHSNITSMFSRSNDYDKPKTSAPVKKNSGSSQTHTKGGT 442
            .   |.|..|     ||:       |...|      .:||         :.|....||...:|..
Yeast   339 L---TPKFAK-----LGF-------GMTMN------DAND---------LAKQQKESQKIAQGPR 373

  Fly   443 STDPVIAQQKFGNSKGFGSDQYFA----SEQSSADVSASLNRFQGSRAISSSDYFGD-------G 496
            .|..:  .:::|..|...|||.|.    .|.::.:....|..|..:.:||||.|||:       |
Yeast   374 YTGRI--AERYGTQKAISSDQLFGRGSFDEAANREAHDKLKTFDNATSISSSSYFGEDKEVDEFG 436

  Fly   497 SPGGTGGNRASS----------VNFSA-PDLDVESVKESVRQGVHKVAGRL 536
            :|..:.|:.|.:          ::|:| .|.:::.:::.|.||..|:...|
Yeast   437 NPINSSGSGAGNFDGRNSNNGFIDFNASADDELQMLRDVVEQGAEKLGSYL 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	51/109 (47%)
GLO3	NP_011048.1	COG5347	9..363	CDD:227651	112/443 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341574
Domainoid	1	1.000	108	1.000	Domainoid score	I1433
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	162	1.000	Inparanoid score	I1051
Isobase	1	0.950	-	0	Normalized mean entropy	S2764
OMA	1	1.010	-	-		QHG52037
OrthoFinder	1	1.000	-	-		FOG0001852
OrthoInspector	1	1.000	-	-		oto99054
orthoMCL	1	0.900	-	-		OOG6_101784
Panther	1	1.100	-	-	LDO	PTHR45686
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R495
SonicParanoid	1	1.000	-	-		X1214
TreeFam	0	0.000	Not matched by this tool.
	14	13.780