DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ArfGAP3 and RPA

DIOPT Version :9

Sequence 1:	NP_001097664.2	Gene:	ArfGAP3 / 40487	FlyBaseID:	FBgn0037182	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_565801.1	Gene:	RPA / 818088	AraportID:	AT2G35210	Length:	395	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	163/547 - (29%)
Similarity:	220/547 - (40%)	Gaps:	186/547 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDTNWTWLQ 79
            |||.:|:|:..||.||||.||.|||:|||||||:|||||||||:||||::|||||||| :|:..|
plant    11 SVFKKLKAKSDNKICFDCNAKNPTWASVTYGIFLCIDCSAVHRSLGVHISFVRSTNLD-SWSSEQ 74

  Fly    80 LRQMQLGGNANAAQFFRAHNCS---TTDAQVKYNSRAAQLYRDKLCAQAQQAMKTHGTKLHLEQT 141
            |:.|..|||..|..||:.:..|   .|:|  ||.||||.||:..|.                ::.
plant    75 LKMMIYGGNNRAQVFFKQYGWSDGGKTEA--KYTSRAADLYKQILA----------------KEV 121

  Fly   142 DKSEGNEAAREEDFFAQCDNEVDFNVQNNNVSKQDPNPP--TVAP--VISVETQQGGAPSVNLLN 202
            .||:..|             |:|.          .|:||  |..|  :.|::|.:....|..|..
plant   122 AKSKAEE-------------ELDL----------PPSPPDSTQVPNGLSSIKTSEALKESNTLKQ 163

  Fly   203 SVVPAAVPSSIGARKVQPKKGGLGAR---KVGGLGATKVKTNFADIEARANAANEMKTSAAAAPV 264
            ...|..||  :..|..:..|..|||:   |.|||||.|:.|               |:|..
plant   164 QEKPDVVP--VSPRISRSVKKPLGAKKTGKTGGLGARKLTT---------------KSSGT---- 207

  Fly   265 VKPQTAEDELETVASMRLAYQELSMQKTREEAKLKTMDPAKAKQ-----MERLGMGFNLRGSDMA 324
                                  |..||..|...::...|..||.     ..|.....|::..:..
plant   208 ----------------------LYDQKPEESVIIQATSPVSAKSARSSFSSRFDYADNVQNREDY 250

  Fly   325 HSALGDMETIQQSAAPKAKLSLLESENFFTDFSLYGNSSSGGGGGGSSEKRESSVGGTSKLDKFE 389
            .|.    :.:...|.||       |..||.
plant   251 MSP----QVVSHVAPPK-------SSGFFE----------------------------------- 269

  Fly   390 LDALGYETIEPIGGSHSNITSMFSRSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVIAQQKFG 454
                  |.:|..||....            ||.||        ||:...:   .||.  |::||.
plant   270 ------EELEMNGGRFQK------------KPITS--------SSKLQIQ---ETDE--ARKKFT 303

  Fly   455 NSKGFGSDQYFASEQSSADVSA--SLNRFQGSRAISSSDYFGDGSPGG-----TGGNRASSVNFS 512
            |:|...|.|||.::.:|||:.|  ||.:|.||.||||:|.||||. |.     |.|:..:.::..
plant   304 NAKSISSAQYFGNDNNSADLEAKSSLKKFSGSSAISSADLFGDGD-GDFPLDLTAGDLLNRLSLQ 367

  Fly   513 APDLDVESVKESVRQGVHKVAGRLSNL 539
            |.. |:.|:|....:...|:....|:|
plant   368 AQQ-DISSLKNMAEETKKKLGSVASSL 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	63/106 (59%)
RPA	NP_565801.1	PLN03114	1..395	CDD:178661	163/547 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	126	1.000	Domainoid score	I1774
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8735
Inparanoid	1	1.050	198	1.000	Inparanoid score	I1325
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1155557at2759
OrthoFinder	1	1.000	-	-		FOG0001852
OrthoInspector	1	1.000	-	-		otm2913
orthoMCL	1	0.900	-	-		OOG6_101784
Panther	1	1.100	-	-	O	PTHR45686
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1214
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830