Protein Alignment ArfGAP3 and git2a

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_005165241.1
• Gene: git2a / 793882
• ZFINID: ZDB-GENE-060526-267
• Length: 804
• Species: Danio rerio
• Alignment Length: 564
• Identity: 114/564 - (20%)
• Similarity: 194/564 - (34%)
• Gaps: 184/564 - (32%)

  Fly    19 RLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDTNWTWLQLRQM 83
            |||   .::.|.||:...|.|:||..|:.||.:|.:|||:||.|.:.||..: :|:|...||:.:
Zfish    14 RLR---NSEVCADCSTSDPRWASVNRGVLICDECCSVHRSLGRHNSQVRHLS-NTSWPPTQLQMV 74

  Fly    84 QLGGNANAAQFFRAHNCSTTDAQVKYNSRAAQLYR----DKLCAQAQQAMKTHGTKLHLEQTD-- 142
                                  |..||:.|..::.    |.....:.:....|..|||..:.|
Zfish    75 ----------------------QTLYNNGANAIWEHTLLDPSSIMSSKRKPNHQDKLHPNKADFI 117

  Fly   143 KSEGNEAA-------REEDFFAQCD--NEVDFNVQNNNVSKQDPNPPTVAPVISVETQ------- 191
            |::....|       |::|..|..|  .::..:|:..|:.       |...::|:..|
Zfish   118 KAKYQMLAYVHRLPCRDDDSTAAADLSKQLHSSVRTGNLE-------TCLRLLSLGAQANYFHPE 175

  Fly   192 QGGAP--SVNLLNSVVPAAVPSSIGARKVQPKKGGLGARKVGGLGATKVKTNFADIEARANAANE 254
            :|..|  .......|..|.:....||....|...|            |...|:|......:.|:.
Zfish   176 KGNTPLHIAAKAGQVCQAELLCVYGADPGAPDSSG------------KTPINYARQAGHQDLADR 228

  Fly   255 MKTSAAAAPVVKPQTAEDELETVASMRLAYQELSMQKTREEAKLKTMDPAKAKQMERLGMGFNLR 319
            :.                |::...:.|||:. |..:|...::....:.|..|.:        |:
Zfish   229 LV----------------EIQYELTDRLAFY-LCGRKPDHKSGQHFIIPQMADR--------NV- 267

  Fly   320 GSDMAHSALGDMETIQQSAAPKAKLSLLESENFFTDFSL--YGNSSSGGGGGGSSEKRESSVGGT 382
                      .:|..:.:.|.|.||..| |::.|.:.::  |
Zfish   268 ----------SVELTEFAKAAKRKLQSL-SDHLFEELAMDVY----------------------- 298

  Fly   383 SKLDKFELDALGYETIEPIGGSHSNITSMFSRSNDYDKPKTSAP-VKKNSGSSQTHTKGGTSTDP 446
            .::|:.|.||:...|     .:||.:.:          ..|..| :..|...|.|..:|
Zfish   299 DEVDRRETDAVWLAT-----QNHSTLVT----------ETTVVPFLPVNPEYSSTRNQG------ 342

  Fly   447 VIAQQKFGNSKGFGSDQYFASEQSS--ADVSASLNRFQGSRAISSS----DYFGDGSPGGTGGNR 505
               :||..        ::.|.|.::  .|:.:...|.|....:.|.    |.|..     :||:|
Zfish   343 ---RQKLA--------RFNAHEFATLVIDILSDAKRRQHGNPVPSPKDNVDVFFK-----SGGSR 391

  Fly   506 --ASSVNFSAPDLDV----ESVKESVRQGVHKVAGRLSNLANDV 543
              :.|.....||.|.    |.....:|.|   .|.|..:|.:|:
Zfish   392 HGSESQEIDQPDYDSVASDEDTDTDLRMG---KADRTKSLDSDL 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	31/105 (30%)
git2a	XP_005165241.1	ArfGap	12..134	CDD:214518	38/145 (26%)
		Ank_2	147..239	CDD:289560	18/126 (14%)
		ANK	<147..230	CDD:238125	17/101 (17%)
		ANK repeat	147..175	CDD:293786	5/34 (15%)
		ANK repeat	177..207	CDD:293786	6/29 (21%)
		GIT_SHD	278..306	CDD:285690	8/51 (16%)
		GIT_SHD	342..369	CDD:285690	7/43 (16%)
		GIT_CC	426..490	CDD:293167	2/7 (29%)
		GIT1_C	632..798	CDD:289013

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900