Protein Alignment ArfGAP3 and Acap2

DIOPT Version :10

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_006522806.1
• Gene: Acap2 / 78618
• MGIID: 1925868
• Length: 816
• Species: Mus musculus
• Alignment Length: 258
• Identity: 59/258 - (22%)
• Similarity: 110/258 - (42%)
• Gaps: 54/258 - (20%)

  Fly     2 ASPAAG------PSKQEI---ESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHR 57
            :||:.|      .||:::   ||...|::..|.|.||.||....|.|:|:..||.:||:||.:||
Mouse   389 SSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNTSCCDCGLADPRWASINLGITLCIECSGIHR 453

  Fly    58 NLGVHLTFVRSTNLDTNWTW--------------------------LQLRQMQLGGNANAAQFFR 96
            :||||.:.|||..||   ||                          :.:::.|.|.......:.|
Mouse   454 SLGVHFSKVRSLTLD---TWEPELLKLMCELGNDVINRVYEAKLEKMGVKKPQPGQRQEKEAYIR 515

  Fly    97 AHNCSTTDAQVKYNSRAAQLYRDK-LCAQAQQAMKTHGTKLHLEQTDKSEGNEAAREEDFFAQCD 160
            |......... ||::..:...::| :.:::.:..:....:..:.....:..::.||.|..|  |.
Mouse   516 AKYVERKFVD-KYSALLSPSEQEKRIISKSCEDQRLSHARASVHTPVAAVTSDEARRESLF--CP 577

  Fly   161 NEVDFNVQNNNVSKQDPNPPTVAPVISVETQQGGAPSVNLLNSVVPAAVPSSIGARKVQPKKG 223
            :|:|     :..|..|    |.:.:.|:::...|   :...:.....::||::.|..:...:|
Mouse   578 DELD-----SLFSYFD----TSSKLRSIKSNDSG---IQQCSEDGRESLPSTVSANSLYEPEG 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap_ArfGap2_3_like	12..127	CDD:350060	38/144 (26%)
Acap2	XP_006522806.1	BAR_ACAP2	18..217	CDD:153322
		PH_ACAP	273..376	CDD:270070
		COG5347	398..>635	CDD:227651	56/249 (22%)
		ArfGap_ACAP2	410..524	CDD:350076	35/116 (30%)
		ANKYR	<648..779	CDD:440430
		ANK repeat	676..709	CDD:293786
		ANK repeat	711..742	CDD:293786