Protein Alignment ArfGAP3 and arfgap2

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_005159305.1
• Gene: arfgap2 / 641490
• ZFINID: ZDB-GENE-051120-177
• Length: 551
• Species: Danio rerio
• Alignment Length: 613
• Identity: 222/613 - (36%)
• Similarity: 313/613 - (51%)
• Gaps: 130/613 - (21%)

  Fly     5 AAGPSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRST 69
            |:.|:|.||.::|.|||:.|.||:|||||||.|:|:|::||:|:|||||.:||:|||||:|:|||
Zfish     2 ASEPNKTEIHTIFKRLRSIPTNKACFDCAAKNPSWASISYGVFLCIDCSGIHRSLGVHLSFIRST 66

  Fly    70 NLDTNWTWLQLRQMQLGGNANAAQFFRAHNCSTTDAQVKYNSRAAQLYRDKLCAQAQQAMKTHGT 134
            .||:||.|.|||.||:||||||..|||.|.|:|.|...||||||||:||:|:...|..|:..:||
Zfish    67 ELDSNWNWFQLRCMQVGGNANAMGFFRQHGCTTNDTNAKYNSRAAQMYREKIRQLANAALSKYGT 131

  Fly   135 KLHLEQTDKSEGNEA-AREEDFFAQ---------------CDNEVDFNV-----QNNNVSKQDPN 178
            .|.::.:..::.:.. .||.|||.:               .|.....||     |:|..:.:.||
Zfish   132 DLWIDSSSCAQPSPVEKRETDFFDEHTQPAISWDMASPSLTDQNGAENVNPQLAQSNPKNSETPN 196

  Fly   179 PPTVAPVISVETQQGGAPSVNLLNSVVPAAV------------------PSSIGARKVQPKKGGL 225
                       ||....||:..|::...|.:                  ||.||.:|....|.||
Zfish   197 -----------TQPEEGPSIEGLSTSPKATIEDSMRLTSEEPQSPKDVKPSIIGKKKPVAAKKGL 250

  Fly   226 GARKVGGLGATKVKT-NFADIEARANAANEMKTSAAAAPVVKPQTAEDELETVASMRLAYQELSM 289
            ||:|  ||||.||.: :|:::|.:|..|.:|:...||.  .|.|..|   ..||||||||:||.:
Zfish   251 GAKK--GLGAQKVSSKSFSEVEKQAQVAEKMREEQAAE--AKKQADE---SIVASMRLAYKELEI 308

  Fly   290 QKTREEAKLKTMDPAKAKQMERLGMGFNLRGSDMAHSALGDMETIQQ------SAAPKAKLSLLE 348
            .:..||.|::.::..|.:|.|||||||..| |.::||.:.:|:.|:|      .::.::||.:.|
Zfish   309 DRKMEEKKMQNLEGKKKEQAERLGMGFGNR-SAVSHSVMAEMQVIEQETPVGVKSSSRSKLDMFE 372

  Fly   349 SENF-----------FTDFSLYGNSSSGGGGGGSS-------EKRESSVGGTSKLDKFELDALGY 395
            ...|           ||....:|:.....||...|       |.::|.|..:|
Zfish   373 EPGFASGPPKYKDNPFTSGDSFGSRWDNDGGSSFSSWALEKEEPKDSEVTISS------------ 425

  Fly   396 ETIEPIGGSHSNITSMFSRSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVIAQQKFGNSKGFG 460
              |:|||          .|.....||:.|.||.::|.                |:|||.|:|...
Zfish   426 --IQPIG----------ERLPSRRKPEVSVPVSESSE----------------ARQKFANAKAIS 462

  Fly   461 SDQYFASEQS-SADVSASLNRFQGSRAISSSDYFGDGSPGGTGGNRASSVNFSAPDLDVESVKES 524
            ||.:|..|.: ..:....|....||.:|||:|.|||||...:|.....||..|.||:      ..
Zfish   463 SDMFFGRESNPEYEAKTRLEGMSGSTSISSADLFGDGSVRPSGSTGFDSVLPSGPDI------AQ 521

  Fly   525 VRQGVHKVAGRLSNLANDVMTSWQDKYG 552
            .:|||..|||:::.|||.||.:.||:||
Zfish   522 FKQGVKTVAGKMAVLANGVMNTIQDRYG 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	69/103 (67%)
arfgap2	XP_005159305.1	PLN03114	1..498	CDD:178661	197/554 (36%)
		ArfGap	13..117	CDD:279720	69/103 (67%)
		TMF_DNA_bd	270..331	CDD:289127	25/65 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I3740
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8735
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2376
OMA	1	1.010	-	-		QHG52037
OrthoDB	1	1.010	-	-		D1155557at2759
OrthoFinder	1	1.000	-	-		FOG0001852
OrthoInspector	1	1.000	-	-		otm24477
orthoMCL	1	0.900	-	-		OOG6_101784
Panther	1	1.100	-	-	O	PTHR45686
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R495
SonicParanoid	1	1.000	-	-		X1214
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870